# Austrian Breast & Colorectal Cancer Study Group

Source: https://onco.cc/companies/abcsg/  
OnCo record `abcsg` (Company). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Austria's academic breast and colorectal trials group, whose bone-targeted and extended endocrine therapy trials changed breast cancer practice.

## Summary

Founded in 1984, ABCSG runs academic trials through Austria's hospitals and partners with the Breast International Group and the US groups on global studies. ABCSG-12 (zoledronic acid with ovarian suppression in premenopausal breast cancer) and ABCSG-18 (adjuvant denosumab) made bone-targeted agents part of adjuvant care, and ABCSG-16 defined how long extended aromatase inhibitor therapy should last. It co-led PALLAS, the adjuvant palbociclib trial, with Alliance Foundation Trials and BIG. Colorectal and pancreatic trials run through the same network.

## Fields

- Kind: Company
- Last checked: 2026-09-09
- Also known as: ABCSG
- Tags: cooperative-group
- HQ: Vienna
- Type: cooperative-group
- Website: https://www.abcsg.org

## Notes

- Adjuvant endocrine and bone-targeted therapy (ABCSG-12, -16, -18)
- PALLAS (adjuvant palbociclib, with Alliance and BIG)
- Colorectal and pancreatic cancer trials

## Sources

- ABCSG: https://www.abcsg.org
- Trials: https://www.abcsg.org/studien/

## Connected records

- drugs: [Palbociclib](https://onco.cc/drugs/palbociclib/)
- cancers: [Colorectal cancer](https://onco.cc/cancers/colorectal/), [HER2-positive breast cancer](https://onco.cc/cancers/breast-her2-positive/), [HR-positive / HER2-negative breast cancer](https://onco.cc/cancers/breast-hr-positive/)
- fronts: [Hormonal Therapy](https://onco.cc/fronts/hormonal/), [Targeted Therapy](https://onco.cc/fronts/targeted-therapy/)
- technologies: [CDK4/6 inhibitors](https://onco.cc/technologies/cdk46-inhibitor/), [Endocrine therapy (SERMs, AIs, SERDs)](https://onco.cc/technologies/endocrine-therapy/)
- companies: [Alliance for Clinical Trials in Oncology](https://onco.cc/companies/alliance-oncology/), [Breast International Group (BIG)](https://onco.cc/companies/big/), [German Breast Group (GBG)](https://onco.cc/companies/gbg/)
- trials: [PALLAS & PENELOPE-B](https://onco.cc/trials/pallas-penelope-b/)
- people: [Christian Singer](https://onco.cc/people/christian-singer/), [Michael Gnant](https://onco.cc/people/michael-gnant/)

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JSON: https://onco.cc/api/v1/entities/abcsg.json