# Advanced Research Projects Agency for Health

Source: https://onco.cc/institutions/arpa-h/  
OnCo record `arpa-h` (Institution). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

The US agency modelled on DARPA that funds high-risk, milestone-driven health programmes, including adaptive cancer therapy, rapid tumour-removal surgery and early detection.

## Summary

Created in 2022 within the Department of Health and Human Services, ARPA-H funds programme managers to run time-limited, milestone-based projects that the NIH grant system does not, with an appropriation of roughly $1.5 billion per year in its first years. Cancer-relevant programmes include ADAPT (adaptive therapies that anticipate tumour evolution), POSEIDON (at-home multi-cancer screening), CUREIT (curative immunotherapy), Precision Surgical Interventions (removing all tumour tissue in one operation) and the Cancer Moonshot-aligned biomanufacturing efforts. It works through ARPANET-H hubs in Massachusetts, Texas and Washington and contracts rather than grants. Its model has drawn interest from other countries designing their own ARPA-style funders.

## Fields

- Kind: Institution
- Last checked: 2026-09-09
- Also known as: ARPA-H
- City: Washington, DC, US
- Type: government
- Website: https://arpa-h.gov

## Sources

- ARPA-H: https://arpa-h.gov
- Programs: https://arpa-h.gov/research-and-funding/programs

## Connected records

- fronts: [Early Detection & Screening](https://onco.cc/fronts/early-detection/), [Immunotherapy](https://onco.cc/fronts/immunotherapy/), [Surgery & Interventional](https://onco.cc/fronts/surgery/)
- technologies: [CAR-T cell therapy](https://onco.cc/technologies/car-t/), [Fluorescence-guided surgery](https://onco.cc/technologies/fluorescence-guided-surgery/), [Multi-cancer early detection (MCED)](https://onco.cc/technologies/mced/)
- institutions: [National Cancer Institute (NIH)](https://onco.cc/institutions/nci/)
- people: [Alicia Jackson](https://onco.cc/people/alicia-jackson/)
- bottlenecks: [Acquired resistance to every therapy](https://onco.cc/bottlenecks/b-resistance/), [Funding follows fashion, not burden](https://onco.cc/bottlenecks/b-funding-allocation/), [Surgery and radiotherapy cure most, get least](https://onco.cc/bottlenecks/b-surgery-radiation-innovation/), [The hardest cancers are found late](https://onco.cc/bottlenecks/b-early-detection/)

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