# CCDC170

Source: https://onco.cc/targets/ccdc170/  
OnCo record `ccdc170` (Target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

CCDC170 (Coiled-coil domain-containing protein 170) is a gene. In the public catalogues the evidence so far is association rather than a proven role. Tied to Breast cancer.

## Summary

Plays a role in Golgi-associated microtubules organisation and stabilisation.

Open Targets scores its association with cancer at 0.55 (direct and indirect evidence; datatypes literature 0.94, genetic association 0.68).

## Fields

- Kind: Target
- Last checked: 2026-09-23
- Also known as: coiled-coil domain containing 170; Coiled-coil domain-containing protein 170; FLJ23305; bA282P11.1; C6orf97
- Tags: cancer-genes-wave
- Symbol: CCDC170
- Class: other
- Biology: Plays a role in Golgi-associated microtubules organisation and stabilisation. Location: Golgi apparatus (UniProt). Locus 6q25.1 (HGNC).
- Where found: Breast cancer: Open Targets association 0.54 with breast cancer (MONDO_0007254)

## Notes

- Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: none stated by the sources. Evidence tier "association-only" is the strongest of those signals.
- Prevalence not recorded: none of the sources gives a positivity rate.

## Sources

- HGNC HGNC:21177: https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:21177
- UniProt Q8IYT3: https://www.uniprot.org/uniprotkb/Q8IYT3/entry
- NCBI Gene 80129: https://www.ncbi.nlm.nih.gov/gene/80129
- Ensembl ENSG00000120262: https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000120262

## Connected records

- collections: [Open Targets Platform](https://onco.cc/collections/open-targets/)
- cancers: [Breast cancer (all types)](https://onco.cc/cancers/breast-cancer/)

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JSON: https://onco.cc/api/v1/entities/ccdc170.json