# CZ CELLxGENE / Human Cell Atlas

Source: https://onco.cc/collections/cellxgene-hca/  
OnCo record `cellxgene-hca` (Collection). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

CELLxGENE and the Human Cell Atlas hold single-cell data from healthy and diseased tissue, browsable and downloadable.

## Summary

CZ CELLxGENE and the Human Cell Atlas hold tens of millions of annotated single cells from healthy and diseased tissue, including tumour microenvironment datasets, all browsable and downloadable. The platform is run by the Chan Zuckerberg Initiative together with the HCA, and the data are released under CC BY. It is the basis for cell-type-level target expression work and immune atlas studies. On OnCo it is linked to the technology Single-cell and spatial profiling, the institutions Chan Zuckerberg Biohub, Max Delbrück Center for Molecular Medicine and Wellcome Sanger Institute, the Virtual cell roadmap and the bottleneck Cold tumours and the immunosuppressive microenvironment, as well as the idea An open foundation model of the cancer cell trained on perturbation data.

## Fields

- Kind: Collection
- Last checked: 2026-09-04
- Also known as: CELLxGENE; CZ CELLxGENE; Human Cell Atlas; HCA; CELLxGENE Census
- URL: https://cellxgene.cziscience.com
- Holds: Tens of millions of single cells with annotations, including tumour microenvironment datasets.
- Licence: CC BY

## Sources

- CZ CELLxGENE / Human Cell Atlas: https://cellxgene.cziscience.com

## Connected records

- technologies: [Single-cell & spatial profiling](https://onco.cc/technologies/single-cell-spatial/)
- bottlenecks: [Cold tumours and the immunosuppressive microenvironment](https://onco.cc/bottlenecks/b-tme-immunosuppression/)
- ideas: [An open foundation model of the cancer cell trained on perturbation data](https://onco.cc/ideas/idea-data-open-cell-foundation-model/), [Link single-cell and spatial tumour atlases to clinical outcomes](https://onco.cc/ideas/idea-data-atlas-to-outcome-linkage/)
- institutions: [Chan Zuckerberg Biohub](https://onco.cc/institutions/cz-biohub/), [Max Delbrück Center for Molecular Medicine](https://onco.cc/institutions/mdc-berlin/), [Wellcome Sanger Institute](https://onco.cc/institutions/wellcome-sanger/)
- roadmaps: [Virtual cell roadmap: from bulk omics to a predictive model of a cancer cell](https://onco.cc/roadmaps/virtual-cell/)
- terms: [AnnData and h5ad files](https://onco.cc/terms/anndata-h5ad/), [Cancer AI vocabulary (CanSim terms map)](https://onco.cc/terms/cancer-ai-vocabulary/), [Single-cell and transcriptome foundation models: UCE, GeneCompass, BulkFormer, BulkRNABert](https://onco.cc/terms/single-cell-foundation-models/), [Single-cell RNA sequencing (scRNA-seq, 10x Chromium)](https://onco.cc/terms/single-cell-rna-seq/), [Uberon anatomy ontology and the Cell Ontology](https://onco.cc/terms/uberon/)

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