# Child-Pugh score

Source: https://onco.cc/terms/child-pugh/  
OnCo record `child-pugh` (Term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A score of how well a damaged liver is still working, from five simple measures (bilirubin, albumin, clotting, fluid in the abdomen, confusion). Class A is well compensated, C is failing. Liver cancer trials almost all require class A.

## Summary

Because hepatocellular carcinoma nearly always arises in cirrhosis, the liver's reserve determines whether a patient can survive resection, tolerate TACE or radioembolisation, or be given systemic therapy, and it competes with the cancer as a cause of death. Almost every phase 3 trial in liver cancer enrolled Child-Pugh A patients only, so evidence in class B is thin. The ALBI grade (albumin and bilirubin only) is a more objective alternative used in modern trials and in the BCLC algorithm.

## Fields

- Kind: Term
- Last checked: 2026-09-09
- Also known as: Child-Pugh; Child-Pugh A; Child-Pugh B; Child-Pugh class; Child–Pugh; ALBI; ALBI grade; liver function reserve

## Sources

- Wikipedia: https://en.wikipedia.org/wiki/Child%E2%80%93Pugh_score
- Wikipedia: https://en.wikipedia.org/wiki/Child%E2%80%93Pugh_score

## Connected records

- terms: [BCLC staging](https://onco.cc/terms/bclc-staging/), [Cirrhosis](https://onco.cc/terms/cirrhosis/), [Hepatectomy (liver resection)](https://onco.cc/terms/hepatectomy/), [Hepatotoxicity (liver enzyme elevation)](https://onco.cc/terms/hepatotoxicity/), [LI-RADS (Liver Imaging Reporting and Data System)](https://onco.cc/terms/li-rads/), [Malignant pleural effusion and ascites](https://onco.cc/terms/pleural-effusion/)
- cancers: [Advanced hepatocellular carcinoma (BCLC C)](https://onco.cc/cancers/hcc-advanced/), [Hepatocellular carcinoma](https://onco.cc/cancers/hcc/)
- fronts: [Diagnostics & Biomarkers](https://onco.cc/fronts/diagnostics/)

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JSON: https://onco.cc/api/v1/entities/child-pugh.json