# Choi criteria (GIST response on CT)

Source: https://onco.cc/terms/choi-criteria/  
OnCo record `choi-criteria` (Term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

The Choi criteria judge whether a gastrointestinal stromal tumour is responding to imatinib by small falls in size or in density on CT, because these tumours often stop growing and go quiet without shrinking much.

## Summary

RECIST is insensitive in GIST treated with imatinib. Choi and colleagues (Journal of Clinical Oncology 2007) compared CT with FDG PET in 40 patients: a fall in tumour size of more than 10% or in tumour density of more than 15% on CT identified PET responders with 97% sensitivity and 100% specificity, against 52% and 100% for RECIST. Good responders on CT at two months had a longer time to progression.

## Fields

- Kind: Term
- Last checked: 2026-11-04
- Also known as: Choi criteria; Choi response criteria

## Sources

- Choi et al., Correlation of CT and PET in patients with metastatic GIST treated at a single institution with imatinib mesylate: proposal of new CT response criteria (J Clin Oncol 2007): https://doi.org/10.1200/jco.2006.07.3049

## Connected records

- terms: [PERCIST (PET response criteria in solid tumours)](https://onco.cc/terms/percist/), [RECIST](https://onco.cc/terms/recist/)
- cancers: [Gastrointestinal stromal tumour (GIST)](https://onco.cc/cancers/gist/)
- technologies: [CT (computed tomography)](https://onco.cc/technologies/ct/), [FDG PET](https://onco.cc/technologies/fdg-pet/)

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