# Constance D. Lehman

Source: https://onco.cc/people/constance-lehman/  
OnCo record `constance-lehman` (Person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Breast radiologist who co-developed the Mirai AI model that predicts breast cancer risk from a mammogram.

## Summary

Constance Lehman co-led with Regina Barzilay the development and validation of Mirai, a deep-learning model that predicts five-year breast cancer risk from mammograms more accurately than clinical risk models across diverse populations, and led the ACRIN studies establishing MRI screening of the contralateral breast. She has led national breast imaging quality initiatives and now works on AI-driven personalised screening.

## Fields

- Kind: Person
- Last checked: 2026-09-10
- Tags: screening; ai; breast
- Role: Professor of Radiology, Harvard Medical School; Co-Director, Breast Imaging Research Center, Massachusetts General Hospital
- Specialisms: Breast imaging; AI risk prediction; Screening MRI; Radiology outcomes

## Sources

- PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Lehman%20CD%5BAuthor%5D%20mammography%20deep%20learning

## Connected records

- cancers: [HR-positive / HER2-negative breast cancer](https://onco.cc/cancers/breast-hr-positive/)
- technologies: [AI in radiology](https://onco.cc/technologies/radiology-ai-screening/), [Mammography & tomosynthesis](https://onco.cc/technologies/mammography/), [MRI](https://onco.cc/technologies/mri/)
- institutions: [Massachusetts General Hospital Cancer Center](https://onco.cc/institutions/mgh/)
- journals: [Science Translational Medicine](https://onco.cc/journals/science-translational-medicine/)

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