# Constellation Pharmaceuticals

Source: https://onco.cc/companies/constellation-pharmaceuticals/  
OnCo record `constellation-pharmaceuticals` (Company). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Constellation Pharmaceuticals developed medicines for cancer that change which genes are switched on in cancer cells. MorphoSys bought it in 2021, and its drugs pelabresib and CPI-0209 (now tulmimetostat) went with it.

## Summary

Constellation Pharmaceuticals was a clinical-stage company developing therapeutics that selectively modulate gene expression for patients with cancer (Third Rock Ventures). MorphoSys AG completed a cash tender offer at $34.00 a share on 15 July 2021, with a total equity value of about $1.7 billion, and Constellation became an indirect wholly owned subsidiary of MorphoSys. The MorphoSys release names Constellation's clinical-stage assets as pelabresib (CPI-0610) and CPI-0209, and also mentions two earlier programmes. Its common stock had traded on Nasdaq as CNST. MorphoSys is itself now part of Novartis.

## Fields

- Kind: Company
- Last checked: 2026-11-04
- Also known as: Constellation Pharmaceuticals, Inc.
- HQ: Cambridge, MA
- Type: biotech

## Notes

- Founding year not stated in the sources read (2008 is Third Rock's year of investment).
- HQ from the SEC EDGAR business address (215 First Street, Cambridge, MA).
- Existing OnCo drug records that came from Constellation: pelabresib and tulmimetostat (CPI-0209); they can link here.
- Targets for pelabresib and CPI-0209 are not stated in the release read, so none set here.

## Sources

- MorphoSys completes acquisition (SEC 6-K exhibit, 15 July 2021): https://www.sec.gov/Archives/edgar/data/1340243/000119312521215759/d193747dex991.htm
- Third Rock Ventures portfolio entry: https://www.thirdrockventures.com/portfolio/constellation

## Connected records

- fronts: [Epigenetic & Transcriptional Therapy](https://onco.cc/fronts/epigenetics/)
- drugs: [Pelabresib](https://onco.cc/drugs/pelabresib/), [Tulmimetostat](https://onco.cc/drugs/tulmimetostat/)
- companies: [MorphoSys (Novartis)](https://onco.cc/companies/morphosys/), [Third Rock Ventures](https://onco.cc/companies/third-rock-ventures/)

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