# Cornelis J. H. van de Velde

Source: https://onco.cc/people/cornelis-van-de-velde/  
OnCo record `cornelis-van-de-velde` (Person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Surgeon who led the Dutch TME trial, proving standardised rectal surgery with radiotherapy cuts local recurrence.

## Summary

Cornelis van de Velde led the Dutch TME trial, which showed that total mesorectal excision taught through a national quality programme combined with short-course preoperative radiotherapy reduces local recurrence in rectal cancer, and the Dutch D1-D2 gastric cancer trial that clarified the role of extended lymphadenectomy. He founded the EURECCA registry programme and has been president of ESSO and ECCO.

## Fields

- Kind: Person
- Last checked: 2026-09-10
- Tags: surgery; colorectal; quality
- Role: Emeritus Professor of Surgical Oncology, Leiden University Medical Center
- Specialisms: Colorectal surgery; Total mesorectal excision; Gastric cancer surgery; Surgical quality

## Sources

- PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=van%20de%20Velde%20CJ%5BAuthor%5D%20rectal%20TME

## Connected records

- cancers: [Colorectal cancer](https://onco.cc/cancers/colorectal/), [Gastric & gastro-oesophageal junction cancer](https://onco.cc/cancers/gastric/)
- institutions: [European Society of Surgical Oncology](https://onco.cc/institutions/esso/), [Leiden University Medical Center](https://onco.cc/institutions/lumc-leiden/)
- key papers: [Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer (Dutch TME trial)](https://onco.cc/key-papers/paper-kapiteijn-dutch-tme-preoperative-radiotherapy-nejm-2001/), [Short-course radiotherapy followed by chemotherapy before total mesorectal excision versus preoperative chemoradiotherapy in locally advanced rectal cancer (RAPIDO)](https://onco.cc/key-papers/paper-bahadoer-rapido-short-course-radiotherapy-lancet-oncol-2021/)
- roadmaps: [Colorectal cancer roadmap: from the adenoma-carcinoma sequence and the first screening trials to total mesorectal excision, oxaliplatin, RAS testing, immunotherapy for mismatch repair-deficient disease, ctDNA-guided treatment and organ preservation](https://onco.cc/roadmaps/colorectal-roadmap/)

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