# NCI Cancer Research Data Commons (CRDC)

Source: https://onco.cc/collections/crdc/  
OnCo record `crdc` (Collection). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

The US National Cancer Institute's cloud system that holds cancer research data from many funded studies, from tumour genetics to scans, and lets researchers search and analyse it without downloading it all.

## Summary

The NCI describes the CRDC as a cloud-based data science infrastructure that provides secure access to a large and expanding collection of cancer research data contributed by NCI and NIH-funded researchers, with tools for analysis and visualisation in the cloud. Its data commons are the Genomic Data Commons (harmonised genomic data including TCGA, TARGET and CPTAC), the Proteomic Data Commons (CPTAC and the International Cancer Proteogenome Consortium), the Imaging Data Commons, the Integrated Canine Data Commons (including the PRECINCT canine immunotherapy trials and the Comparative Oncology Program), the Clinical and Translational Data Commons, the Population Science Data Commons and a General Commons. Core services are the Cancer Data Aggregator for querying across commons, the Data Commons Framework for authentication, authorisation and permanent identifiers, and the Seven Bridges Cancer Genomics Cloud developed by Velsera. A single CRDC Submission Portal supports data sharing under the NIH Data Management and Sharing Policy. The NCI Moonshot page lists its construction among the Moonshot's accomplishments.

## Fields

- Kind: Collection
- Last checked: 2026-11-04
- Also known as: CRDC; Cancer Research Data Commons
- Tags: research-funding; data
- URL: https://datacommons.cancer.gov/
- Holds: NCI and NIH-funded cancer research data across linked data commons: genomic (GDC: TCGA, TARGET, CPTAC), proteomic (PDC), imaging (IDC), canine trials (ICDC), clinical and translational studies (CTDC), population science (PSDC) and a General Commons, with the Cancer Data Aggregator, the Data Commons Framework for access control and identifiers, and the Seven Bridges Cancer Genomics Cloud for analysis.
- Licence: Mixed: open and controlled-access tiers set by each commons and study

## Notes

- Component list from the CRDC home page, read on 4 November 2026. Data volumes were not stated there and are not given.

## Sources

- NCI Cancer Research Data Commons: https://datacommons.cancer.gov/

## Connected records

- collections: [Childhood Cancer Data Initiative (CCDI)](https://onco.cc/collections/ccdi/), [CPTAC (Clinical Proteomic Tumor Analysis Consortium)](https://onco.cc/collections/cptac/), [Human Tumor Atlas Network (HTAN)](https://onco.cc/collections/htan/), [NCI Imaging Data Commons (IDC)](https://onco.cc/collections/imaging-data-commons/), [TCGA / NCI Genomic Data Commons](https://onco.cc/collections/tcga-gdc/)
- companies: [Velsera (Seven Bridges and Pierian)](https://onco.cc/companies/velsera/)
- institutions: [National Cancer Institute (NIH)](https://onco.cc/institutions/nci/)
- bottlenecks: [Data silos](https://onco.cc/bottlenecks/b-data-silos/)

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