# CTAG1B

Source: https://onco.cc/targets/ctag1b/  
OnCo record `ctag1b` (Target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

CTAG1B (Cancer/testis antigen 1) is a gene. The public catalogues list it as a drug target and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Multiple myeloma.

## Summary

UniProt has no function text for P78358; HGNC names it "cancer/testis antigen 1B".

CIViC holds 2 clinical evidence items and 0 assertions across 2 variants, naming Letetresgene Autoleucel. In OnCo, 1 product record names it (Letetresgene autoleucel).

## Fields

- Kind: Target
- Last checked: 2026-09-23
- Also known as: cancer/testis antigen 1B; Cancer/testis antigen 1; NY-ESO-1; LAGE2B; LAGE2A; ESO1; CT6.1; CTAG1
- Tags: cancer-genes-wave
- Symbol: CTAG1B
- Class: other
- Biology: UniProt has no function text for P78358; HGNC names it "cancer/testis antigen 1B". Location: Cytoplasm (UniProt). Locus Xq28 (HGNC).
- Where found: Multiple myeloma: CIViC evidence names this disease

## Notes

- Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: CIViC lists 1 therapies; CIViC holds 2 clinical evidence items on its variants. Evidence tier "clinical-evidence" is the strongest of those signals.
- Prevalence not recorded: none of the sources gives a positivity rate.
- Diseases the sources name that have no OnCo cancer page yet, so they are not linked: Myxoid Liposarcoma.

## Sources

- HGNC HGNC:2491: https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:2491
- UniProt P78358: https://www.uniprot.org/uniprotkb/P78358/entry
- NCBI Gene 1485: https://www.ncbi.nlm.nih.gov/gene/1485
- Ensembl ENSG00000184033: https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000184033

## Connected records

- collections: [CIViC](https://onco.cc/collections/civic/)
- cancers: [Multiple myeloma](https://onco.cc/cancers/multiple-myeloma/)
- drugs: [Letetresgene autoleucel](https://onco.cc/drugs/letetresgene-autoleucel/)
- trials: [Multi-center Study of TBI-1301 (INN: Mipetresgene Autoleucel; Mip-cel) in Patients With NY-ESO-1 Positive Synovial Sarcoma](https://onco.cc/trials/nct07174427/)

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JSON: https://onco.cc/api/v1/entities/ctag1b.json