# CTAG2

Source: https://onco.cc/targets/ctag2/  
OnCo record `ctag2` (Target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

CTAG2 (Cancer/testis antigen 2) is a gene. The public catalogues list it as a drug target and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Multiple myeloma.

## Summary

UniProt has no function text for O75638; HGNC names it "cancer/testis antigen 2".

CIViC holds 1 clinical evidence item and 0 assertions across 1 variant, naming Letetresgene Autoleucel.

## Fields

- Kind: Target
- Last checked: 2026-09-23
- Also known as: cancer/testis antigen 2; Cancer/testis antigen 2; LAGE-1; CAMEL; LAGE1; ESO2; MGC3803; MGC138724; CT6.2a; CT6.2b; LAGE-1a; LAGE-1b
- Tags: cancer-genes-wave
- Symbol: CTAG2
- Class: other
- Biology: UniProt has no function text for O75638; HGNC names it "cancer/testis antigen 2". Locus Xq28 (HGNC).
- Where found: Multiple myeloma: CIViC evidence names this disease

## Notes

- Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: CIViC lists 1 therapies; CIViC holds 1 clinical evidence items on its variants. Evidence tier "clinical-evidence" is the strongest of those signals.
- Prevalence not recorded: none of the sources gives a positivity rate.

## Sources

- HGNC HGNC:2492: https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:2492
- UniProt O75638: https://www.uniprot.org/uniprotkb/O75638/entry
- NCBI Gene 30848: https://www.ncbi.nlm.nih.gov/gene/30848
- Ensembl ENSG00000126890: https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000126890

## Connected records

- collections: [CIViC](https://onco.cc/collections/civic/)
- cancers: [Multiple myeloma](https://onco.cc/cancers/multiple-myeloma/)

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JSON: https://onco.cc/api/v1/entities/ctag2.json