# CTONG 2508 (ADAPT Lung)

Source: https://onco.cc/trials/ctong-2508/  
OnCo record `ctong-2508` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A Chinese lung cancer trial that uses blood tests for leftover cancer to decide how much immunotherapy to give after surgery.

## Summary

CTONG 2508, ADAPT Lung (NCT07120698), is a single-arm phase 2 trial of residual disease-guided adjuvant sintilimab in patients with stage II to IIIB non-small cell lung cancer who did not achieve a pathological complete response after neoadjuvant immunotherapy with chemotherapy, at the Third People's Hospital of Chengdu and Guangdong Provincial People's Hospital. The primary endpoint is two-year event-free survival; primary completion is estimated for June 2029.

## Fields

- Kind: Trial
- Status: recruiting
- Last checked: 2026-11-04
- Also known as: ADAPT Lung; CTONG2508
- Registry id: NCT07120698
- Phase: 2
- Setting: Stage II to IIIB non-small cell lung cancer without pathological complete response after neoadjuvant immunotherapy plus chemotherapy: adjuvant sintilimab adapted to residual disease results
- Sponsor: Guangdong Association of Clinical Trials
- Enrolled: 115

## Sources

- ClinicalTrials.gov NCT07120698: https://clinicaltrials.gov/study/NCT07120698

## Connected records

- cancers: [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/)
- technologies: [Immune checkpoint inhibitors](https://onco.cc/technologies/checkpoint-inhibitor/), [MRD / molecular residual disease testing](https://onco.cc/technologies/mrd-testing/)
- drugs: [Sintilimab](https://onco.cc/drugs/sintilimab/)
- companies: [Chinese Thoracic Oncology Group](https://onco.cc/companies/ctong/)
- institutions: [Guangdong Provincial People's Hospital](https://onco.cc/institutions/guangdong-provincial-peoples-hospital/)
- terms: [Circulating tumour DNA (ctDNA)](https://onco.cc/terms/ctdna/), [Minimal / molecular residual disease (MRD)](https://onco.cc/terms/mrd/), [Tumour-informed versus tumour-naive ctDNA assays](https://onco.cc/terms/tumour-informed-assay/)

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JSON: https://onco.cc/api/v1/entities/ctong-2508.json