# David L. Porter

Source: https://onco.cc/people/david-porter/  
OnCo record `david-porter` (Person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Treated the first adult CLL patients with CAR-T and reported a decade of durable remissions.

## Summary

David L. Porter is the Jodi Fisher Horowitz Professor in Leukemia Care Excellence and Director of Cell Therapy and Transplant at the Abramson Cancer Center, University of Pennsylvania. He is known for treating the first adult patients with chronic lymphocytic leukaemia using CAR-T cells, leading the clinical side of Penn's first CTL019 studies. His selected paper reports decade-long leukaemia remissions with persistence of CD4-positive CAR T cells in long-term responders. He now leads cell therapy and stem cell transplant at Penn, spanning CAR-T for leukaemia and allogeneic transplantation.

## Fields

- Kind: Person
- Last checked: 2026-09-08
- Role: Jodi Fisher Horowitz Professor in Leukemia Care Excellence; Director, Cell Therapy and Transplant
- Specialisms: CAR-T; Chronic lymphocytic leukaemia; Stem cell transplant

## Sources

- Penn profile: https://www.pennmedicine.org/providers/profile/david-porter
- PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Porter%20DL%5BAuthor%5D

## Connected records

- cancers: [Acute lymphoblastic leukaemia](https://onco.cc/cancers/all-leukemia/), [Chronic lymphocytic leukaemia](https://onco.cc/cancers/cll/)
- technologies: [Allogeneic stem cell transplantation](https://onco.cc/technologies/allogeneic-hsct/), [CAR-T cell therapy](https://onco.cc/technologies/car-t/)
- targets: [CD19](https://onco.cc/targets/cd19/)
- drugs: [Tisagenlecleucel](https://onco.cc/drugs/tisagenlecleucel/)
- institutions: [Abramson Cancer Center, University of Pennsylvania](https://onco.cc/institutions/penn-abramson/)
- people: [Emily Whitehead](https://onco.cc/people/emily-whitehead/)
- key papers: [Maude 2014: CD19 CAR-T cells produce complete remission in 27 of 30 children and adults with relapsed ALL](https://onco.cc/key-papers/paper-maude-ctl019-all-nejm-2014/)

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