# DISCOVER (Galleri over time in people with symptoms)

Source: https://onco.cc/trials/discover-galleri-symptomatic/  
OnCo record `discover-galleri-symptomatic` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A small Dana-Farber study of what the Galleri test finds, and misses, when it is used repeatedly in people who have symptoms.

## Summary

DISCOVER (NCT07390643) is a single-arm interventional study sponsored by Dana-Farber Cancer Institute. Its primary outcomes are the type, incidence and stage of cancers found by Galleri and of cancers it did not detect.

The registry record, read on 29 October 2026, gives its status as not yet recruiting, with an estimated 100 participants, a planned start in July 2026 and primary completion expected on 31 January 2027.

## Fields

- Kind: Trial
- Status: planned
- Last checked: 2026-10-29
- Also known as: DISCOVER study; DISCOVERY
- Registry id: NCT07390643
- Phase: not-applicable
- Setting: People with symptoms that could be cancer at Dana-Farber Cancer Institute, tested with Galleri over time
- Sponsor: Dana-Farber Cancer Institute
- Enrolled: 100

## Sources

- ClinicalTrials.gov NCT07390643: https://clinicaltrials.gov/study/NCT07390643

## Connected records

- fronts: [Early Detection & Screening](https://onco.cc/fronts/early-detection/)
- technologies: [Liquid biopsy (ctDNA)](https://onco.cc/technologies/liquid-biopsy/), [Multi-cancer early detection (MCED)](https://onco.cc/technologies/mced/)
- drugs: [Galleri](https://onco.cc/drugs/galleri/)
- companies: [GRAIL](https://onco.cc/companies/grail/)
- institutions: [Dana-Farber Brigham Cancer Center](https://onco.cc/institutions/dana-farber/)

---
JSON: https://onco.cc/api/v1/entities/discover-galleri-symptomatic.json