# Elicio Therapeutics

Source: https://onco.cc/companies/elicio-therapeutics/  
OnCo record `elicio-therapeutics` (Company). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Small biotech developing lymph-node-targeted KRAS vaccines for pancreatic and colorectal cancer.

## Summary

Elicio Therapeutics, based in Boston and listed as ELTX, is a small biotechnology company developing lymph-node-targeted vaccines against mutant KRAS for pancreatic and colorectal cancer. Its lead candidate, ELI-002 7P, is an amphiphile vaccine designed to carry mutant KRAS peptides to lymph nodes, and the AMPLIFY-7P phase 2 trial missed its primary endpoint in June 2026, after which the company said its phase 3 strategy was being refined. OnCo links it to pancreatic ductal adenocarcinoma and to the bottleneck of undruggable drivers, since KRAS vaccination is one route around the difficulty of inhibiting the protein directly. Whether a shared-antigen KRAS vaccine can succeed in a phase 3 where the phase 2 did not is the open question. ELI-002 7P has its own page.

## Fields

- Kind: Company
- Last checked: 2026-09-06
- HQ: Boston, MA
- Type: biotech
- Website: https://elicio.com
- Ticker: ELTX

## Sources

- Official website: https://elicio.com

## Connected records

- cancers: [Metastatic pancreatic ductal adenocarcinoma](https://onco.cc/cancers/metastatic-pdac/), [Pancreatic ductal adenocarcinoma](https://onco.cc/cancers/pancreatic/), [Resectable pancreatic ductal adenocarcinoma](https://onco.cc/cancers/resectable-pdac/)
- drugs: [ELI-002 7P](https://onco.cc/drugs/eli-002-7p/)
- trials: [AMPLIFY-7P](https://onco.cc/trials/amplify-7p/)
- roadmaps: [Pancreatic cancer roadmap: from Whipple's operation to gemcitabine, FOLFIRINOX, adjuvant chemotherapy, PARP inhibition, KRAS inhibition, vaccines and the surveillance question](https://onco.cc/roadmaps/pancreatic-roadmap/)
- bottlenecks: [The undruggable drivers](https://onco.cc/bottlenecks/b-undruggable-targets/)

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