# Ferumoxtran-10 (Sinerem, lymph node MRI contrast)

Source: https://onco.cc/drugs/ferumoxtran-10/  
OnCo record `ferumoxtran-10` (Imaging agent). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

An iron-based MRI dye designed to show whether lymph nodes contain cancer. Its European application was withdrawn in 2007 and it is not authorised there.

## Summary

The EMA register lists Sinerem (iron oxide, Guerbet, EMEA/H/C/000801) with the status "Application withdrawn", the withdrawal dated 13 December 2007. The WHO index lists iron oxide nanoparticles as ATC V08CB03 among superparamagnetic contrast media.

## Fields

- Kind: Imaging agent
- Status: withdrawn
- Last checked: 2026-11-04
- Also known as: ferumoxtran-10; Sinerem; iron oxide nanoparticles
- Tags: contrast-agents-gaps-2026-11; diagnostic
- Brand: Sinerem
- Modality: Iron oxide nanoparticle contrast agent for lymph node MRI (application withdrawn in Europe)
- Mechanism: Ultrasmall iron oxide nanoparticles, a superparamagnetic contrast medium, change the MRI signal of tissues that take them up; the product was developed to image lymph nodes.

## Sources

- EMA: Sinerem: https://www.ema.europa.eu/en/medicines/human/EPAR/sinerem
- WHO ATC index V08CB: superparamagnetic contrast media: https://atcddd.fhi.no/atc_ddd_index/?code=V08CB&showdescription=no

## Connected records

- technologies: [Gadolinium-based and other MRI contrast agents](https://onco.cc/technologies/gadolinium-based-contrast-agents/), [MRI](https://onco.cc/technologies/mri/)
- companies: [Guerbet](https://onco.cc/companies/guerbet/)

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JSON: https://onco.cc/api/v1/entities/ferumoxtran-10.json