# FGF6

Source: https://onco.cc/targets/fgf6/  
OnCo record `fgf6` (Target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

FGF6 (Fibroblast growth factor 6) is a gene. In the public catalogues the evidence so far is association rather than a proven role.

## Summary

Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration.

Open Targets scores its association with cancer at 0.61 (direct and indirect evidence; datatypes literature 0.33, affected pathway 0.98).

## Fields

- Kind: Target
- Last checked: 2026-09-23
- Also known as: fibroblast growth factor 6; Fibroblast growth factor 6
- Tags: cancer-genes-wave
- Symbol: FGF6
- Class: other
- Biology: Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration. Location: Secreted, extracellular space (UniProt). Locus 12p13.32 (HGNC).

## Notes

- Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: none stated by the sources. Evidence tier "association-only" is the strongest of those signals.
- Prevalence not recorded: none of the sources gives a positivity rate.

## Sources

- HGNC HGNC:3684: https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3684
- UniProt P10767: https://www.uniprot.org/uniprotkb/P10767/entry
- NCBI Gene 2251: https://www.ncbi.nlm.nih.gov/gene/2251
- Ensembl ENSG00000111241: https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000111241

## Connected records

- collections: [Open Targets Platform](https://onco.cc/collections/open-targets/)

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JSON: https://onco.cc/api/v1/entities/fgf6.json