# FGF9

Source: https://onco.cc/targets/fgf9/  
OnCo record `fgf9` (Target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

FGF9 (Fibroblast growth factor 9) is a gene. In the public catalogues the evidence so far is association rather than a proven role.

## Summary

Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumours.

Open Targets scores its association with cancer at 0.67 (direct and indirect evidence; datatypes literature 0.98, affected pathway 0.99, animal model 0.85, genetic association 0.29).

## Fields

- Kind: Target
- Last checked: 2026-09-23
- Also known as: fibroblast growth factor 9; Fibroblast growth factor 9
- Tags: cancer-genes-wave
- Symbol: FGF9
- Class: other
- Biology: Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumours. Location: Secreted (UniProt). Locus 13q12.11 (HGNC).

## Notes

- Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: none stated by the sources. Evidence tier "association-only" is the strongest of those signals.
- Prevalence not recorded: none of the sources gives a positivity rate.

## Sources

- HGNC HGNC:3687: https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3687
- UniProt P31371: https://www.uniprot.org/uniprotkb/P31371/entry
- NCBI Gene 2254: https://www.ncbi.nlm.nih.gov/gene/2254
- Ensembl ENSG00000102678: https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000102678

## Connected records

- collections: [Open Targets Platform](https://onco.cc/collections/open-targets/)

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JSON: https://onco.cc/api/v1/entities/fgf9.json