# FGFR1OP2

Source: https://onco.cc/targets/fgfr1op2/  
OnCo record `fgfr1op2` (Target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

FGFR1OP2 (FGFR1 oncogene partner 2) is a gene. The public catalogues list it as a fusion partner, and the evidence so far is association rather than a proven role. Tied to Leukaemia.

## Summary

May be involved in wound healing pathway.

Open Targets scores its association with cancer at 0.60 (direct and indirect evidence; datatypes literature 0.22, affected pathway 0.95, animal model 0.56, genetic association 0.03).

## Fields

- Kind: Target
- Last checked: 2026-09-23
- Also known as: FGFR1 oncogene partner 2; DKFZp564O1863
- Tags: cancer-genes-wave
- Symbol: FGFR1OP2
- Class: other
- Biology: May be involved in wound healing pathway. Location: Cytoplasm (UniProt). Locus 12p11.23 (HGNC).
- Where found: Leukaemia: Open Targets association 0.55 with leukaemia (MONDO_0005059)

## Notes

- Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: UniProt disease notes describe a translocation or gene fusion involving the gene. Evidence tier "association-only" is the strongest of those signals.
- Prevalence not recorded: none of the sources gives a positivity rate.

## Sources

- HGNC HGNC:23098: https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:23098
- UniProt Q9NVK5: https://www.uniprot.org/uniprotkb/Q9NVK5/entry
- NCBI Gene 26127: https://www.ncbi.nlm.nih.gov/gene/26127
- Ensembl ENSG00000111790: https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000111790

## Connected records

- collections: [Open Targets Platform](https://onco.cc/collections/open-targets/)
- cancers: [Leukaemia (all types)](https://onco.cc/cancers/leukaemia/)

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JSON: https://onco.cc/api/v1/entities/fgfr1op2.json