# FS-207

Source: https://onco.cc/drugs/fs-207/  
OnCo record `fs-207` (Treatment). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

FS-207 is an experimental oral small molecule from Fushi Biotechnology, in phase 1 trials for MSI-high advanced solid tumours.

## Summary

FS-207 is an oral small molecule (tablet) from Fushi Biotechnology. Targets the WRN helicase; developed for solid tumours with high microsatellite instability (MSI-H). Its furthest stage is phase 1, for MSI-high advanced solid tumours. ClinicalTrials.gov registers it in one study linked below. NMPA implied clinical trial approval April 2026 (company news); phase 1a/1b NCT07593144 not yet recruiting. Whether it works in people has not been established unless a trial below reports it.

## Fields

- Kind: Treatment
- Status: phase-1
- Last checked: 2026-11-03
- Tags: pipeline; ctgov-ingest
- Code: FS-207
- Modality: Oral small molecule (tablet)
- Mechanism: Targets the WRN helicase; developed for solid tumours with high microsatellite instability (MSI-H).

## Sources

- Fushi Biotechnology: foresightbiopharm.com: https://www.foresightbiopharm.com/en/pipeline.html
- Fushi Biotechnology: foresightbiopharm.com: https://www.foresightbiopharm.com/
- Fushi Biotechnology: clinicaltrials.gov: https://clinicaltrials.gov/api/v2/studies/NCT07593144
- ClinicalTrials.gov: trials of FS-207: https://clinicaltrials.gov/search?intr=FS-207

## Connected records

- cancers: [Metastatic cancer (cancer that has spread)](https://onco.cc/cancers/metastatic-cancer/)
- targets: [WRN helicase (MSI-high cancers)](https://onco.cc/targets/wrn/)
- companies: [Fushi Biotechnology](https://onco.cc/companies/fushi-biotechnology/)
- trials: [A Single-Arm, Open-Label Phase Ia/Ib Clinical Trial Evaluating the Safety, Tolerability, Pharmacokinetic Profile, and Preliminary Efficacy of FS-207 in Patients With Advanced Solid Tumors With High Microsatellite Instability (MSI-H)](https://onco.cc/trials/nct07593144/)

---
JSON: https://onco.cc/api/v1/entities/fs-207.json