# Funda Meric-Bernstam

Source: https://onco.cc/people/funda-meric-bernstam/  
OnCo record `funda-meric-bernstam` (Person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Funda Meric-Bernstam runs the world's largest phase 1 programme and led the tumour-agnostic HER2 ADC study.

## Summary

Funda Meric-Bernstam is Chair of Investigational Cancer Therapeutics at MD Anderson Cancer Center, where she runs the world's largest phase 1 programme. A surgical oncologist turned early-drug-development leader, she directs MD Anderson's Institute for Personalized Cancer Therapy and chaired DESTINY-PanTumor02, the trial that led to the tumour-agnostic approval of trastuzumab deruxtecan for HER2 IHC 3+ solid tumours. Her papers report the primary results of the DESTINY-PanTumor02 phase II trial of trastuzumab deruxtecan in HER2-expressing solid tumours and the feasibility of large-scale genomic testing to enrol patients onto genomically matched trials. Her work spans precision oncology, comprehensive genomic profiling and companion diagnostics.

## Fields

- Kind: Person
- Last checked: 2026-09-08
- Role: Chair, Investigational Cancer Therapeutics, MD Anderson
- Specialisms: Phase 1 trials; Precision oncology; HER2

## Sources

- MD Anderson faculty: https://faculty.mdanderson.org/search?q=Funda%20Meric-Bernstam
- PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Meric-Bernstam%20F%5BAuthor%5D
- Google Scholar: https://scholar.google.com/scholar?q=Funda%20Meric-Bernstam

## Connected records

- technologies: [Companion diagnostics](https://onco.cc/technologies/companion-diagnostic/), [Comprehensive genomic profiling](https://onco.cc/technologies/cgp/)
- targets: [HER2](https://onco.cc/targets/her2/)
- drugs: [Trastuzumab deruxtecan](https://onco.cc/drugs/trastuzumab-deruxtecan/)
- institutions: [MD Anderson Cancer Center](https://onco.cc/institutions/md-anderson/)
- trials: [DESTINY-PanTumor02](https://onco.cc/trials/destiny-pantumor02/), [MyPathway](https://onco.cc/trials/mypathway/)

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