# GOLGA4

Source: https://onco.cc/targets/golga4/  
OnCo record `golga4` (Target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

GOLGA4 (Golgin subfamily A member 4) is a gene. In the public catalogues the evidence so far is association rather than a proven role.

## Summary

Involved in vesicular trafficking at the Golgi apparatus level. May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1. Involved in endosome-to-Golgi trafficking.

Open Targets scores its association with cancer at 0.54 (direct and indirect evidence; datatypes literature 0.68, affected pathway 0.76, genetic association 0.38).

## Fields

- Kind: Target
- Last checked: 2026-09-23
- Also known as: golgin A4; Golgin subfamily A member 4; golgin-245; GCP2; p230; golgin-240
- Tags: cancer-genes-wave
- Symbol: GOLGA4
- Class: other
- Biology: Involved in vesicular trafficking at the Golgi apparatus level. May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi network through its interaction with MACF1. Involved in endosome-to-Golgi trafficking. Location: Cytoplasm; Golgi apparatus membrane; Golgi apparatus, trans-Golgi network membrane (UniProt). Locus 3p22.2 (HGNC).

## Notes

- Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: none stated by the sources. Evidence tier "association-only" is the strongest of those signals.
- Prevalence not recorded: none of the sources gives a positivity rate.

## Sources

- HGNC HGNC:4427: https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:4427
- UniProt Q13439: https://www.uniprot.org/uniprotkb/Q13439/entry
- NCBI Gene 2803: https://www.ncbi.nlm.nih.gov/gene/2803
- Ensembl ENSG00000144674: https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000144674

## Connected records

- collections: [Open Targets Platform](https://onco.cc/collections/open-targets/)

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JSON: https://onco.cc/api/v1/entities/golga4.json