# GOLGA5

Source: https://onco.cc/targets/golga5/  
OnCo record `golga5` (Target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

GOLGA5 (Golgin subfamily A member 5) is a gene. The public catalogues list it as a fusion partner, and the evidence so far is association rather than a proven role.

## Summary

Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.

Open Targets scores its association with cancer at 0.56 (direct and indirect evidence; datatypes literature 0.10, genetic association 0.00, somatic mutation 0.92).

## Fields

- Kind: Target
- Last checked: 2026-09-23
- Also known as: golgin A5; Golgin subfamily A member 5; ret-II; golgin-84; rfg5; GOLIM5
- Tags: cancer-genes-wave
- Symbol: GOLGA5
- Class: other
- Biology: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport. Location: Golgi apparatus membrane (UniProt). Locus 14q32.12 (HGNC).

## Notes

- Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: UniProt disease notes describe a translocation or gene fusion involving the gene. Evidence tier "association-only" is the strongest of those signals.
- Prevalence not recorded: none of the sources gives a positivity rate.

## Sources

- HGNC HGNC:4428: https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:4428
- UniProt Q8TBA6: https://www.uniprot.org/uniprotkb/Q8TBA6/entry
- NCBI Gene 9950: https://www.ncbi.nlm.nih.gov/gene/9950
- Ensembl ENSG00000066455: https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000066455

## Connected records

- collections: [Open Targets Platform](https://onco.cc/collections/open-targets/)

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JSON: https://onco.cc/api/v1/entities/golga5.json