# GOLGB1

Source: https://onco.cc/targets/golgb1/  
OnCo record `golgb1` (Target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

GOLGB1 (Golgin subfamily B member 1) is a gene. In the public catalogues the evidence so far is association rather than a proven role.

## Summary

May participate in forming intercisternal cross-bridges of the Golgi complex.

Open Targets scores its association with cancer at 0.60 (direct and indirect evidence; datatypes literature 0.27, affected pathway 0.95, animal model 0.69, genetic association 0.00).

## Fields

- Kind: Target
- Last checked: 2026-09-23
- Also known as: golgin B1; Golgin subfamily B member 1; GCP372; giantin; GOLIM1
- Tags: cancer-genes-wave
- Symbol: GOLGB1
- Class: other
- Biology: May participate in forming intercisternal cross-bridges of the Golgi complex. Location: Golgi apparatus membrane (UniProt). Locus 3q13.33 (HGNC).

## Notes

- Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: none stated by the sources. Evidence tier "association-only" is the strongest of those signals.
- Prevalence not recorded: none of the sources gives a positivity rate.

## Sources

- HGNC HGNC:4429: https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:4429
- UniProt Q14789: https://www.uniprot.org/uniprotkb/Q14789/entry
- NCBI Gene 2804: https://www.ncbi.nlm.nih.gov/gene/2804
- Ensembl ENSG00000173230: https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000173230

## Connected records

- collections: [Open Targets Platform](https://onco.cc/collections/open-targets/)

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JSON: https://onco.cc/api/v1/entities/golgb1.json