# Helix Hereditary Comprehensive Cancer Panel

Source: https://onco.cc/drugs/helix-hereditary-cancer/  
OnCo record `helix-hereditary-cancer` (Test). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Helix's test of 70 genes linked to inherited cancer risk, registered with the US genetic testing registry in 2026.

## Summary

Registered in the NIH Genetic Testing Registry as GTR000619734.3 by Helix, Inc. (CLIA 05D2117342; created 20 March 2026, updated 25 March 2026): 70 genes, including the breast, ovarian, Lynch and polyposis genes, BAP1, DICER1, FLCN, MEN1, RET, VHL, the SDH genes, NF1, NF2 and SMARCB1. GTR records it as a test developed by the laboratory; it is not among the FDA-authorised hereditary cancer products.

## Fields

- Kind: Test
- Status: established
- Last checked: 2026-11-04
- Tags: test; hereditary
- Brand: Helix Hereditary Comprehensive Cancer Panel
- Modality: Germline hereditary cancer sequencing panel (laboratory-developed test)
- Mechanism: Next-generation sequencing of 70 hereditary cancer genes in germline DNA.

## Sources

- NIH Genetic Testing Registry GTR000619734.3: https://www.ncbi.nlm.nih.gov/gtr/tests/619734/
- NIH Genetic Testing Registry data file (test_version.gz): https://ftp.ncbi.nlm.nih.gov/pub/GTR/data/test_version.gz

## Connected records

- technologies: [Germline (hereditary) testing](https://onco.cc/technologies/germline-testing/)
- targets: [BAP1](https://onco.cc/targets/bap1/), [BRCA1 / BRCA2 (HRD)](https://onco.cc/targets/brca/), [DICER1](https://onco.cc/targets/dicer1/), [FLCN](https://onco.cc/targets/flcn/), [MLH1](https://onco.cc/targets/mlh1/), [MSH2](https://onco.cc/targets/msh2/), [PALB2](https://onco.cc/targets/palb2/), [VHL](https://onco.cc/targets/vhl/)
- terms: [Birt-Hogg-Dubé syndrome](https://onco.cc/terms/birt-hogg-dube-syndrome/), [Bloom syndrome](https://onco.cc/terms/bloom-syndrome/), [Hereditary cancer syndromes](https://onco.cc/terms/hereditary-cancer-syndromes/), [Lynch syndrome](https://onco.cc/terms/lynch-syndrome/)

---
JSON: https://onco.cc/api/v1/entities/helix-hereditary-cancer.json