# Hopec Pharma

Source: https://onco.cc/companies/hopec-pharma/  
OnCo record `hopec-pharma` (Company). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Hopec Pharma is an Israeli company developing an immune treatment for early bladder cancer made from an inactivated, genetically modified E. coli bacterium. It is in a first trial in people whose cancer came back after BCG or chemotherapy in the bladder.

## Summary

Hopec Pharma, of Givat Shmuel, Israel, develops Inactivated UPEC-FimON, an immunotherapy based on a genetically modified uropathogenic Escherichia coli for non-muscle invasive bladder cancer; Estee Rosen is co-founder and chief executive. The company describes partnerships with the Hebrew University, Hadassah and Sheba. Its first registered cancer trial, NCT07881666, an open-label multicentre phase 1 study of intravesical inactivated UPEC-FimON in non-muscle invasive urothelial carcinoma after failure of BCG or intravesical chemotherapy, at Kfar Saba, Jerusalem and Ramat Gan, was posted on ClinicalTrials.gov in October 2026; the registry gives its start as October 2025.

## Fields

- Kind: Company
- Last checked: 2026-10-29
- Also known as: HOPEC Pharma; Hopec-Pharma
- HQ: Givat Shmuel
- Type: biotech
- Website: https://www.hopec-pharma.com/

## Notes

- The company website calls the product a 'non-intravesical immunotherapy', while the registry record describes intravesical administration; the registry is followed here. Founding year and financing not stated on the pages read. Read on 29 October 2026.

## Sources

- Official website: https://www.hopec-pharma.com/
- About Hopec Pharma: https://www.hopec-pharma.com/about
- ClinicalTrials.gov: phase 1 trial of UPEC-FimON (NCT07881666): https://clinicaltrials.gov/study/NCT07881666

## Connected records

- cancers: [Non-muscle-invasive bladder cancer](https://onco.cc/cancers/non-muscle-invasive-bladder-cancer/)
- fronts: [Immunotherapy](https://onco.cc/fronts/immunotherapy/)
- technologies: [Intravesical therapy (BCG, chemotherapy, devices, gene and viral therapy)](https://onco.cc/technologies/bcg-and-intravesical-therapy/)

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