# Insightec

Source: https://onco.cc/companies/insightec/  
OnCo record `insightec` (Company). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

MR-guided focused ultrasound company, with oncology use in blood-brain-barrier opening for brain tumours.

## Summary

Insightec, based in Haifa, is the MR-guided focused ultrasound company whose oncology relevance lies in opening the blood-brain barrier so that drugs can reach brain tumours. Its Exablate Neuro system is established in essential tremor, Exablate Prostate treats prostate tissue, and its blood-brain barrier opening trials aim at drug delivery in glioblastoma. OnCo links it to glioma and glioblastoma, to focused ultrasound and histotripsy, focused-ultrasound blood-brain barrier opening and sonodynamic therapy, to Sunnybrook and the UVA cancer centre, and to ideas such as a standard platform for getting drugs into the brain and an ultrasound-assisted blood test instead of a brain biopsy. The brain as a barrier and sanctuary is the bottleneck it exists to breach. Whether transient barrier opening improves outcomes, not just drug levels, is the open question.

## Fields

- Kind: Company
- Last checked: 2026-09-04
- HQ: Haifa
- Type: devices
- Website: https://www.insightec.com

## Sources

- Wikipedia: https://en.wikipedia.org/wiki/Insightec
- Official website: https://www.insightec.com

## Connected records

- fronts: [Devices & Physical Therapies](https://onco.cc/fronts/devices/), [Surgery & Interventional](https://onco.cc/fronts/surgery/)
- technologies: [Focused ultrasound & histotripsy](https://onco.cc/technologies/hifu-histotripsy/), [Focused-ultrasound blood-brain barrier opening](https://onco.cc/technologies/bbb-focused-ultrasound/), [Sonodynamic therapy](https://onco.cc/technologies/sonodynamic-therapy/), [Transcranial focused ultrasound systems (Exablate Neuro, SonoCloud)](https://onco.cc/technologies/transcranial-focused-ultrasound-systems/)
- trials: [Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric Diffuse Intrinsic Pontine Gliomas (DIPG)](https://onco.cc/trials/nct05630209/), [Blood Brain Barrier (BBB) Disruption Using Exablate Focused Ultrasound With Doxorubicin for Treatment of Pediatric DIPG](https://onco.cc/trials/nct05615623/), [Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets](https://onco.cc/trials/nct05317858/)
- cancers: [Glioma & glioblastoma](https://onco.cc/cancers/glioblastoma/)
- bottlenecks: [The brain: barrier and sanctuary](https://onco.cc/bottlenecks/b-brain-delivery/)
- ideas: [A standard platform to get drugs into the brain: focused ultrasound plus shuttle-engineered therapeutics](https://onco.cc/ideas/idea-moon-brain-delivery-platform/), [Device-agnostic public trials of ablation technologies against surgery](https://onco.cc/ideas/idea-fund-ablation-versus-surgery-trials/), [Open the barrier so engineered immune cells can enter the brain](https://onco.cc/ideas/idea-bio2-fus-for-cell-entry/), [Ultrasound-assisted blood test instead of a brain biopsy](https://onco.cc/ideas/idea-bio2-sonobiopsy/)
- institutions: [Sunnybrook Odette Cancer Centre](https://onco.cc/institutions/sunnybrook-odette/), [UVA Comprehensive Cancer Center](https://onco.cc/institutions/uva-cancer-center/)
- roadmaps: [Devices and physical therapies roadmap: heat and light → electric fields and focused sound → drug-releasing implants](https://onco.cc/roadmaps/devices-roadmap/)

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JSON: https://onco.cc/api/v1/entities/insightec.json