# INV-9956

Source: https://onco.cc/drugs/inv-9956/  
OnCo record `inv-9956` (Treatment). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

INV-9956 is an experimental CYP11A1 inhibitor from Shenzhen Ionova Life Sciences, in phase 2 trials for metastatic castration-resistant prostate cancer.

## Summary

INV-9956 is a CYP11A1 inhibitor from Shenzhen Ionova Life Sciences. A CYP11A1 inhibitor for castration-resistant prostate cancer, given with dexamethasone and fludrocortisone acetate in the trial. Its furthest stage is phase 2, for metastatic castration-resistant prostate cancer. ClinicalTrials.gov registers it in one study linked below. Company announced first patient dosed in the phase II trial (news dated 2025-12-05); FDA Fast Track for advanced mCRPC (news dated 2025-11-03). Registry trial is phase 1/2, recruiting. Whether it works in people has not been established unless a trial below reports it.

## Fields

- Kind: Treatment
- Status: phase-2
- Last checked: 2026-11-03
- Tags: pipeline; ctgov-ingest
- Code: INV-9956
- Modality: CYP11A1 inhibitor
- Mechanism: A CYP11A1 inhibitor for castration-resistant prostate cancer, given with dexamethasone and fludrocortisone acetate in the trial.

## Sources

- Shenzhen Ionova Life Sciences: ionovabio.com: https://www.ionovabio.com/en/companynews
- Shenzhen Ionova Life Sciences: ionovabio.com: https://www.ionovabio.com/en/companynews
- Shenzhen Ionova Life Sciences: clinicaltrials.gov: https://clinicaltrials.gov/api/v2/studies/NCT06609005
- ClinicalTrials.gov: trials of INV-9956: https://clinicaltrials.gov/search?intr=INV-9956

## Connected records

- cancers: [Metastatic castration-resistant prostate cancer](https://onco.cc/cancers/prostate-mcrpc/)
- targets: [CYP11A1 (cholesterol side-chain cleavage enzyme)](https://onco.cc/targets/cyp11a1/)
- companies: [Shenzhen Ionova Life Sciences](https://onco.cc/companies/shenzhen-ionova-life-sciences/)
- trials: [A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of INV-9956 in Adult Patients With Advanced Metastatic Castration Resistant Prostate Cancer](https://onco.cc/trials/nct06609005/)

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JSON: https://onco.cc/api/v1/entities/inv-9956.json