# Invitae Multi-Cancer Panel

Source: https://onco.cc/drugs/invitae-multi-cancer-panel/  
OnCo record `invitae-multi-cancer-panel` (Test). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Invitae's broad blood test for inherited cancer risk across many cancer types, now sold under Labcorp.

## Summary

Registered in the NIH Genetic Testing Registry as GTR000528909.5 by Invitae (80 genes, entry last updated 7 June 2017), including the solid-tumour predisposition genes and haematological genes such as CEBPA, GATA2 and RUNX1, and DICER1, SMARCB1, PHOX2B, WT1 and GPC3 for childhood tumours. A version with RNA analysis, the Invitae Multi-Cancer + RNA Panel (GTR000597547.2, 2022), lists 63 genes. GTR records it as a test developed by the laboratory; it is not among the FDA-authorised products, unlike Invitae's Common Hereditary Cancers Panel. Labcorp bought select Invitae assets in 2024.

## Fields

- Kind: Test
- Status: established
- Last checked: 2026-11-04
- Tags: test; hereditary
- Brand: Invitae Multi-Cancer Panel
- Modality: Germline hereditary cancer sequencing panel (laboratory-developed test)
- Mechanism: Next-generation sequencing of germline DNA across a broad multi-cancer gene list.

## Sources

- NIH Genetic Testing Registry GTR000528909.5: https://www.ncbi.nlm.nih.gov/gtr/tests/528909/
- NIH Genetic Testing Registry GTR000597547.2: https://www.ncbi.nlm.nih.gov/gtr/tests/597547/
- NIH Genetic Testing Registry data file (test_version.gz): https://ftp.ncbi.nlm.nih.gov/pub/GTR/data/test_version.gz

## Connected records

- drugs: [Invitae Common Hereditary Cancers Panel](https://onco.cc/drugs/invitae-common-hereditary-cancers-panel/)
- technologies: [Germline (hereditary) testing](https://onco.cc/technologies/germline-testing/)
- targets: [BRCA1 / BRCA2 (HRD)](https://onco.cc/targets/brca/), [DICER1](https://onco.cc/targets/dicer1/), [GATA2](https://onco.cc/targets/gata2/), [PALB2](https://onco.cc/targets/palb2/), [RUNX1](https://onco.cc/targets/runx1/), [SMARCB1](https://onco.cc/targets/smarcb1/), [TP53](https://onco.cc/targets/tp53/), [WT1](https://onco.cc/targets/wt1/)
- companies: [Invitae](https://onco.cc/companies/invitae/)
- terms: [Beckwith-Wiedemann syndrome](https://onco.cc/terms/beckwith-wiedemann-syndrome/), [Bloom syndrome](https://onco.cc/terms/bloom-syndrome/), [Carney complex](https://onco.cc/terms/carney-complex/), [Hereditary cancer syndromes](https://onco.cc/terms/hereditary-cancer-syndromes/)

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JSON: https://onco.cc/api/v1/entities/invitae-multi-cancer-panel.json