# Journal of Clinical Investigation

Source: https://onco.cc/journals/jci/  
OnCo record `jci` (Journal). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

The Journal of Clinical Investigation is a century-old physician-scientist journal, free to read, publishing mechanistic disease biology including tumour immunology, metabolism and early CAR-T science.

## Summary

Monthly and fully free to read, published by the non-profit American Society for Clinical Investigation. Publishes translational studies across medicine with a strong cancer immunology and haematology component, including early CAR-T and tumour-microenvironment work. JCI Insight is its open-access sister.

## Fields

- Kind: Journal
- Last checked: 2026-09-09
- Also known as: JCI; J Clin Invest
- Publisher: American Society for Clinical Investigation
- Scope: translational medicine
- Access: open-access

## Sources

- JCI Insight: https://insight.jci.org

## Connected records

- terms: [Preclinical](https://onco.cc/terms/preclinical/)
- key papers: [A PET imaging agent for evaluating PARP-1 expression in ovarian cancer](https://onco.cc/key-papers/paper-makvandi-j-clin-invest/), [CD19 CAR-T cells of defined CD4+:CD8+ composition in adult B cell ALL patients](https://onco.cc/key-papers/paper-cd19-all-leukemia-j-clin-invest-2016/), [Genomics of lethal prostate cancer at diagnosis and castration resistance](https://onco.cc/key-papers/paper-mateo-genomics-lethal-prostate-diagnosis-castration-resistance-jci-2020/), [Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies](https://onco.cc/key-papers/paper-lehmann-tnbc-subtypes-jci-2011/), [Molecular profiling stratifies diverse phenotypes of treatment-refractory metastatic castration-resistant prostate cancer](https://onco.cc/key-papers/paper-labrecque-mcrpc-phenotypes-jci-2019/), [NTRK and RET fusion-directed therapy in pediatric thyroid cancer yields a tumor response and radioiodine uptake](https://onco.cc/key-papers/paper-navigate-j-clin-invest-2021/), [Spatially distinct tumor immune microenvironments stratify triple-negative breast cancers](https://onco.cc/key-papers/paper-gruosso-tnbc-spatial-immune-microenvironments-jci-2019/), [Targeting the extrinsic apoptotic pathway in cancer: lessons learned and future directions](https://onco.cc/key-papers/paper-ashkenazi-j-clin-invest/)
- people: [Hans-Peter Kiem](https://onco.cc/people/hans-peter-kiem/), [Stanley R. Riddell](https://onco.cc/people/stanley-riddell/), [Yoram G. Weiss](https://onco.cc/people/yoram-weiss/)

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JSON: https://onco.cc/api/v1/entities/jci.json