# Akhil Kapoor

Source: https://onco.cc/people/kapoor-akhil/  
OnCo record `kapoor-akhil` (Person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

First author of METRO PLUS, the Varanasi trial that doubled survival in advanced head and neck cancer by adding cheap oral metronomic drugs to standard chemotherapy.

## Summary

Akhil Kapoor is a medical oncologist at Tata Memorial Centre's Varanasi hospitals and first author of METRO PLUS (JCO Global Oncology 2026), a randomised trial of 238 patients with advanced unresectable head and neck cancer in which paclitaxel-carboplatin plus oral metronomic chemotherapy gave a median overall survival of 10 months against 5 months with chemotherapy alone (hazard ratio 0.54). His work continues the Tata Memorial tradition of trials designed for the drugs and budgets available to most of the world's patients.

## Fields

- Kind: Person
- Last checked: 2026-09-10
- Role: Medical oncologist, Homi Bhabha Cancer Hospital and MPMMCC, Varanasi (Tata Memorial Centre)
- Specialisms: Head and neck cancer; Metronomic chemotherapy; Pragmatic trials; Global oncology

## Sources

- Tata Memorial Centre: https://tmc.gov.in
- PubMed author search: https://pubmed.ncbi.nlm.nih.gov/?term=Kapoor%20A%5BAuthor%5D%20Varanasi%20head%20and%20neck%20metronomic

## Connected records

- cancers: [Head and neck squamous cell carcinoma](https://onco.cc/cancers/head-and-neck/)
- technologies: [Cytotoxic chemotherapy](https://onco.cc/technologies/cytotoxic-chemotherapy/)
- drugs: [Carboplatin](https://onco.cc/drugs/carboplatin/), [Methotrexate](https://onco.cc/drugs/methotrexate/), [Paclitaxel / nab-paclitaxel](https://onco.cc/drugs/paclitaxel/)
- institutions: [Homi Bhabha Cancer Hospital and Mahamana Pandit Madan Mohan Malaviya Cancer Centre, Varanasi](https://onco.cc/institutions/homi-bhabha-cancer-hospital-varanasi/), [Tata Memorial Centre](https://onco.cc/institutions/tata-memorial/)
- trials: [METRO PLUS (Tata Memorial Centre, Varanasi)](https://onco.cc/trials/metro-plus-varanasi/)

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