# Zonghai Li

Source: https://onco.cc/people/li-zonghai/  
OnCo record `li-zonghai` (Person). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Zonghai Li moved CAR-T therapy from blood cancers into stomach cancer, founding CARsgen and developing satri-cel, the first CAR-T approved for a solid tumour.

## Summary

At the Shanghai Cancer Institute Li developed GPC3-directed CAR-T for liver cancer and the Claudin 18.2 CAR-T CT041, whose phase 1 results (Nature Medicine 2022) and randomised phase 2 trial in gastric cancer led to NMPA approval as satricabtagene autoleucel in 2025; CARsgen's fully human BCMA CAR-T zevorcabtagene autoleucel was approved in 2024. He founded CARsgen in 2014 and listed it in Hong Kong in 2021.

## Fields

- Kind: Person
- Last checked: 2026-09-10
- Also known as: 李宗海
- Tags: china
- Role: Founder, Chairman and CEO, CARsgen Therapeutics; Professor, Shanghai Cancer Institute, Renji Hospital
- Specialisms: CAR-T for solid tumours; Claudin 18.2; GPC3; Antibody engineering

## Sources

- CARsgen Therapeutics: https://www.carsgen.com/en/
- PubMed author search: https://pubmed.ncbi.nlm.nih.gov/?term=Li%20Z%5BAuthor%5D%20claudin18.2%20CAR-T%20gastric

## Connected records

- cancers: [Gastric & gastro-oesophageal junction cancer](https://onco.cc/cancers/gastric/), [Hepatocellular carcinoma](https://onco.cc/cancers/hcc/), [Multiple myeloma](https://onco.cc/cancers/multiple-myeloma/)
- technologies: [CAR-T cell therapy](https://onco.cc/technologies/car-t/)
- targets: [BCMA](https://onco.cc/targets/bcma/), [Claudin 18.2](https://onco.cc/targets/cldn18-2/), [Glypican-3](https://onco.cc/targets/gpc3/)
- drugs: [Satricabtagene autoleucel](https://onco.cc/drugs/satricabtagene-autoleucel/), [Zevorcabtagene autoleucel](https://onco.cc/drugs/zevorcabtagene-autoleucel/)
- companies: [CARsgen Therapeutics](https://onco.cc/companies/carsgen/)
- institutions: [Renji Hospital, Shanghai Jiao Tong University](https://onco.cc/institutions/renji-hospital/)

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JSON: https://onco.cc/api/v1/entities/li-zonghai.json