# Menarini Silicon Biosystems

Source: https://onco.cc/companies/menarini-silicon-biosystems/  
OnCo record `menarini-silicon-biosystems` (Company). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

The Menarini group's diagnostics arm that owns CellSearch, the only regulator-cleared circulating tumour cell test, and DEPArray, an instrument that picks out single cells from a sample for sequencing.

## Summary

Silicon Biosystems was founded in Bologna as a spin-out from the University of Bologna to commercialise DEPArray, a dielectrophoresis-based instrument that isolates individual cells from a mixed sample so they can be sequenced or analysed one at a time. The Menarini group acquired it in 2013 and in 2017 bought the CellSearch circulating tumour cell system from Janssen Diagnostics, uniting enumeration of circulating tumour cells with single-cell recovery. The company sells the instruments and reagents to hospital and research laboratories and runs a service laboratory in the United States; its main customers are pharmaceutical trials that use circulating tumour cell counts and single-cell analysis as biomarkers.

## Fields

- Kind: Company
- Last checked: 2026-09-17
- Also known as: Silicon Biosystems; CellSearch; DEPArray
- HQ: Castel Maggiore (Bologna), Italy
- Type: diagnostics
- Website: https://www.siliconbiosystems.com

## Sources

- Official website: https://www.siliconbiosystems.com
- CellSearch: https://www.cellsearchctc.com

## Connected records

- cancers: [Breast cancer (all types)](https://onco.cc/cancers/breast-cancer/), [Colorectal cancer](https://onco.cc/cancers/colorectal/), [Prostate cancer](https://onco.cc/cancers/prostate/)
- technologies: [CellSearch circulating tumour cell count](https://onco.cc/technologies/cellsearch-ctc-count/), [Circulating tumour cell capture](https://onco.cc/technologies/ctc-capture/), [Liquid biopsy (ctDNA)](https://onco.cc/technologies/liquid-biopsy/), [Single-cell & spatial profiling](https://onco.cc/technologies/single-cell-spatial/)
- companies: [Menarini / Stemline](https://onco.cc/companies/menarini/)

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