# Methylprednisolone

Source: https://onco.cc/drugs/methylprednisolone/  
OnCo record `methylprednisolone` (Treatment). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

Methylprednisolone is a steroid medicine given into a vein. The WHO lists it as an essential medicine for treating lymphoid leukaemia and Burkitt lymphoma, as part of the treatment plan.

## Summary

Methylprednisolone is on the WHO Model List of Essential Medicines in the cancer section on hormones and antihormones, as 40 mg and 125 mg vials for intravenous injection (as sodium succinate), for lymphoid leukaemia and for Burkitt lymphoma including Burkitt leukaemia. The EML status history records it as first added in 2011 for lymphoid leukaemia (TRS 965) and added in 2021 for Burkitt lymphoma (TRS 1035). The US label for the injection (Solu-Medrol, distributed by Pharmacia & Upjohn Company LLC, a subsidiary of Pfizer Inc) lists, under neoplastic diseases, the palliative management of leukaemias and lymphomas. The corpus's other glucocorticoids are dexamethasone, prednisone and hydrocortisone.

## Fields

- Kind: Treatment
- Status: approved
- Last checked: 2026-11-03
- Also known as: methylprednisolone; methylprednisolone sodium succinate; Solu-Medrol
- Tags: universe-gap; who-eml
- Brand: Solu-Medrol
- Modality: Corticosteroid (glucocorticoid; injection)
- Mechanism: An anti-inflammatory glucocorticoid (US label); the label lists the palliative management of leukaemias and lymphomas among its uses.
- Approvals: WHO 2011: Essential Medicines List, hormones and antihormones: lymphoid leukaemia (2011, TRS 965); Burkitt lymphoma including Burkitt leukaemia (2021, TRS 1035)

## Sources

- WHO eEML: Methylprednisolone: https://list.essentialmeds.org/medicines/114
- US label: Solu-Medrol (DailyMed): https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7271310c-7764-4812-aa30-a5e90987c7a9

## Connected records

- drugs: [Dexamethasone](https://onco.cc/drugs/dexamethasone/), [Hydrocortisone](https://onco.cc/drugs/hydrocortisone/), [Prednisone](https://onco.cc/drugs/prednisone/)
- cancers: [Acute lymphoblastic leukaemia](https://onco.cc/cancers/all-leukemia/), [Burkitt lymphoma](https://onco.cc/cancers/burkitt-lymphoma/)
- targets: [Glucocorticoid receptor (NR3C1)](https://onco.cc/targets/glucocorticoid-receptor/)

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JSON: https://onco.cc/api/v1/entities/methylprednisolone.json