# MIR218-1

Source: https://onco.cc/targets/mir218-1/  
OnCo record `mir218-1` (Target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

MIR218-1 (microRNA 218-1) is a gene. The public catalogues list it as a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Colorectal cancer and Pancreatic ductal adenocarcinoma.

## Summary

UniProt has no function text for this gene; HGNC names it "microRNA 218-1".

CIViC holds 3 clinical evidence items and 0 assertions across 2 variants.

## Fields

- Kind: Target
- Last checked: 2026-09-23
- Also known as: microRNA 218-1; hsa-mir-218-1; MIRN218-1
- Tags: cancer-genes-wave
- Symbol: MIR218-1
- Class: other
- Biology: UniProt has no function text for this gene; HGNC names it "microRNA 218-1". Locus 4p15.31 (HGNC).
- Where found: Colorectal cancer: CIViC evidence names this disease; Pancreatic ductal adenocarcinoma: CIViC evidence names this disease

## Notes

- Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: CIViC holds 3 clinical evidence items on its variants. Evidence tier "clinical-evidence" is the strongest of those signals.
- Prevalence not recorded: none of the sources gives a positivity rate.

## Sources

- HGNC HGNC:31595: https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:31595
- NCBI Gene 407000: https://www.ncbi.nlm.nih.gov/gene/407000
- Ensembl ENSG00000207732: https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000207732

## Connected records

- collections: [CIViC](https://onco.cc/collections/civic/)
- cancers: [Colorectal cancer](https://onco.cc/cancers/colorectal/), [Pancreatic ductal adenocarcinoma](https://onco.cc/cancers/pancreatic/)

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JSON: https://onco.cc/api/v1/entities/mir218-1.json