# MYEOV

Source: https://onco.cc/targets/myeov/  
OnCo record `myeov` (Target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

MYEOV (Myeloma-overexpressed gene protein) is a gene that drives cell growth when it is altered. The public catalogues list it as an oncogene driver, and it is called a cancer driver by mutation analysis of patient cohorts. Tied to Prostate cancer.

## Summary

UniProt has no function text for Q96EZ4; HGNC names it "myeloma overexpressed".

Open Targets scores its association with cancer at 0.52 (direct and indirect evidence; datatypes literature 0.91, genetic association 0.62, somatic mutation 0.23). IntOGen calls it a driver in 1 cohort (1 activating, 0 loss-of-function), covering Prostate Adenocarcinoma.

## Fields

- Kind: Target
- Last checked: 2026-09-23
- Also known as: myeloma overexpressed; Myeloma-overexpressed gene protein
- Tags: cancer-genes-wave
- Symbol: MYEOV
- Class: oncogene
- Biology: UniProt has no function text for Q96EZ4; HGNC names it "myeloma overexpressed". Locus 11q13.3 (HGNC).
- Where found: Prostate cancer: IntOGen driver in 1 cohort (PRAD)

## Notes

- Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: IntOGen calls it an activating (Act) driver in 1 cohort. Evidence tier "cohort-driver" is the strongest of those signals.
- Prevalence not recorded: none of the sources gives a positivity rate.

## Sources

- HGNC HGNC:7563: https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:7563
- UniProt Q96EZ4: https://www.uniprot.org/uniprotkb/Q96EZ4/entry
- NCBI Gene 26579: https://www.ncbi.nlm.nih.gov/gene/26579
- Ensembl ENSG00000172927: https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000172927

## Connected records

- collections: [IntOGen](https://onco.cc/collections/intogen/), [Open Targets Platform](https://onco.cc/collections/open-targets/)
- cancers: [Prostate cancer](https://onco.cc/cancers/prostate/)

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JSON: https://onco.cc/api/v1/entities/myeov.json