# Combination Chemotherapy With or Without G-CSF in Treating Older Patients With Acute Myeloid Leukemia

Source: https://onco.cc/trials/nct00002719/  
OnCo record `nct00002719` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of Filgrastim, Amsacrine, Carmustine, Cytarabine, Etoposide, Idarubicin and Mitoxantrone in Leukaemia, run by European Organisation for Research and Treatment of Cancer - EORTC, completed.

## Summary

Combination Chemotherapy With or Without G-CSF in Treating Older Patients With Acute Myeloid Leukemia is a phase 3 interventional study registered as NCT00002719 by European Organisation for Research and Treatment of Cancer - EORTC, with 500 participants recorded, started 1995-12 and reaching its primary completion in 2001-11. Interventions recorded: filgrastim, amsacrine, carmustine, cytarabine, etoposide, idarubicin, mitoxantrone hydrochloride, peripheral blood stem cell transplantation. Conditions recorded: Leukemia, Neutropenia.

Linked to the drug Amsacrine because the registry names it among its interventions and Leukaemia among its conditions. Registry record only: no result has been read by an editor.

## Fields

- Kind: Trial
- Status: completed
- Last checked: 2026-09-22
- Tags: pipeline; ctgov-ingest
- Registry id: NCT00002719
- Phase: 3
- Setting: RANDOMIZED PHASE III STUDY TO EVALUATE THE VALUE OF rHuG-CSF IN INDUCTION AND OF AN ORAL SCHEDULE AS CONSOLIDATION TREATMENT IN ELDERLY PATIENTS WITH ACUTE MYELOGENOUS LEUMEKIA (AML-13 PROTOCOL)
- Sponsor: European Organisation for Research and Treatment of Cancer - EORTC
- Enrolled: 500

## Sources

- ClinicalTrials.gov NCT00002719: https://clinicaltrials.gov/study/NCT00002719

## Connected records

- cancers: [Leukaemia (all types)](https://onco.cc/cancers/leukaemia/)
- drugs: [Amsacrine](https://onco.cc/drugs/amsacrine/), [Carmustine](https://onco.cc/drugs/carmustine/), [Cytarabine](https://onco.cc/drugs/cytarabine/), [Etoposide](https://onco.cc/drugs/etoposide/), [Filgrastim (G-CSF)](https://onco.cc/drugs/filgrastim/), [Idarubicin](https://onco.cc/drugs/idarubicin/), [Mitoxantrone](https://onco.cc/drugs/mitoxantrone/)

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JSON: https://onco.cc/api/v1/entities/nct00002719.json