# Bleomycin, Doxycycline, or Talc in Treating Patients With Malignant Pleural Effusions

Source: https://onco.cc/trials/nct00002872/  
OnCo record `nct00002872` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of Bleomycin and Talc in Metastatic cancer, run by Eastern Cooperative Oncology Group, completed.

## Summary

Bleomycin, Doxycycline, or Talc in Treating Patients With Malignant Pleural Effusions is a phase 3 interventional study registered as NCT00002872 by Eastern Cooperative Oncology Group, with 480 participants recorded, started 1997-01-10 and reaching its primary completion in 2003-02. Interventions recorded: bleomycin sulfate, doxycycline, talc. Conditions recorded: Metastatic Cancer.

Linked to the drug Talc because the registry names it among its interventions and Metastatic cancer among its conditions. Registry record only: no result has been read by an editor.

## Fields

- Kind: Trial
- Status: completed
- Last checked: 2026-09-22
- Tags: pipeline; ctgov-ingest
- Registry id: NCT00002872
- Phase: 3
- Setting: A PROSPECTIVE RANDOMIZED TRIAL OF BLEOMYCIN VS. DOXYCYCLINE VS. TALC FOR THE INTRAPLEURAL TREATMENT OF MALIGNANT PLEURAL EFFUSIONS
- Sponsor: Eastern Cooperative Oncology Group
- Enrolled: 480

## Sources

- ClinicalTrials.gov NCT00002872: https://clinicaltrials.gov/study/NCT00002872

## Connected records

- cancers: [Metastatic cancer (cancer that has spread)](https://onco.cc/cancers/metastatic-cancer/)
- drugs: [Bleomycin](https://onco.cc/drugs/bleomycin/), [Talc (intrapleural)](https://onco.cc/drugs/talc-sclerosant/)

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