# Hormone Therapy With or Without Docetaxel And Estramustine in Treating Patients With Prostate Cancer That is Locally Advanced or At High Risk of Relapse

Source: https://onco.cc/trials/nct00055731/  
OnCo record `nct00055731` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of Bicalutamide, Goserelin / leuprolide, Docetaxel, Estramustine and Aspirin in Prostate cancer, run by UNICANCER, completed.

## Summary

Hormone Therapy With or Without Docetaxel And Estramustine in Treating Patients With Prostate Cancer That is Locally Advanced or At High Risk of Relapse is a phase 3 interventional study registered as NCT00055731 by UNICANCER, with 413 participants recorded, started 2002-11-14 and reaching its primary completion in 2010-12-21. Interventions recorded: bicalutamide, Goserelin Acetate, docetaxel, Estramustine phosphate sodium, acetylsalicylic acid, conventional surgery, radiation therapy. Conditions recorded: Prostate Cancer.

Linked to the drug Estramustine because the registry names it among its interventions and Prostate cancer among its conditions. Registry record only: no result has been read by an editor.

## Fields

- Kind: Trial
- Status: completed
- Last checked: 2026-09-22
- Tags: pipeline; ctgov-ingest
- Registry id: NCT00055731
- Phase: 3
- Setting: Phase III Randomized Study Of Adjuvant Hormonal Therapy With And Without Docetaxel And Estramustine In Patients With Advanced Prostate Cancer Or With A High Risk Of Relapse
- Sponsor: UNICANCER
- Enrolled: 413

## Sources

- ClinicalTrials.gov NCT00055731: https://clinicaltrials.gov/study/NCT00055731

## Connected records

- cancers: [Prostate cancer](https://onco.cc/cancers/prostate/)
- drugs: [Aspirin](https://onco.cc/drugs/aspirin/), [Bicalutamide](https://onco.cc/drugs/bicalutamide/), [Docetaxel](https://onco.cc/drugs/docetaxel/), [Estramustine](https://onco.cc/drugs/estramustine/), [Goserelin / leuprolide (ovarian function suppression)](https://onco.cc/drugs/goserelin/)

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