# Phase II Study of Gamma Knife Radiosurgery and Temozolomide for Brain Metastases

Source: https://onco.cc/trials/nct00582075/  
OnCo record `nct00582075` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of Gamma Knife in Brain metastases, run by University of Alabama at Birmingham, completed.

## Summary

Phase II Study of Gamma Knife Radiosurgery and Temozolomide for Brain Metastases is a phase 2 interventional study registered as NCT00582075 by University of Alabama at Birmingham, with 25 participants recorded, started 2002-07 and reaching its primary completion in 2008-10. Interventions recorded: temozolomide. Conditions recorded: Cancer, Brain Metastases.

Linked to the technology Gamma Knife because the registry's title names it ("gamma knife") and Brain metastases among its conditions. Registry record only: no result has been read by an editor.

## Fields

- Kind: Trial
- Status: completed
- Last checked: 2026-09-22
- Tags: pipeline; ctgov-ingest
- Registry id: NCT00582075
- Phase: 2
- Setting: Phase II Study of Gamma Knife Radiosurgery and Temozolomide (Temodar) for Newly Diagnosed Brain Metastases
- Sponsor: University of Alabama at Birmingham
- Enrolled: 25

## Sources

- ClinicalTrials.gov NCT00582075: https://clinicaltrials.gov/study/NCT00582075

## Connected records

- cancers: [Brain metastases (secondary brain tumours)](https://onco.cc/cancers/secondary-brain-tumours/)
- technologies: [Gamma Knife](https://onco.cc/technologies/gamma-knife/)
- drugs: [Temozolomide](https://onco.cc/drugs/temozolomide/)

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