# Six vs 12 Months of Trastuzumab With Docetaxel Following FEC as Adjuvant Treatment in N+ Breast Cancer

Source: https://onco.cc/trials/nct00615602/  
OnCo record `nct00615602` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of Docetaxel, Trastuzumab, Epirubicin, Cyclophosphamide, Fluorouracil, Lenograstim and Pegfilgrastim in Breast cancer, run by Hellenic Oncology Research Group, completed.

## Summary

Six vs 12 Months of Trastuzumab With Docetaxel Following FEC as Adjuvant Treatment in N+ Breast Cancer is a phase 3 interventional study registered as NCT00615602 by Hellenic Oncology Research Group, with 489 participants recorded, started 2004-10 and reaching its primary completion in 2012-05. Interventions recorded: Docetaxel, Trastuzumab, Epirubicin, Cyclophosphamide, 5-fluoruracil, Granulocyte-colony stimulating growth factor, Trastuzumab. Conditions recorded: Breast Cancer.

Linked to the drug Lenograstim because the registry names it among its interventions and Breast cancer among its conditions. Registry record only: no result has been read by an editor.

## Fields

- Kind: Trial
- Status: completed
- Last checked: 2026-09-22
- Tags: pipeline; ctgov-ingest
- Registry id: NCT00615602
- Phase: 3
- Setting: A Multicenter Randomized Phase III Study Comparing 6 Versus 12 Months of Trastuzumab in Combination With Dose Dense Docetaxel Following FE75C as Adjuvant Treatment of Women With Axillary Lymph Node Positive Breast Cancer Over-expressing HER2
- Sponsor: Hellenic Oncology Research Group
- Enrolled: 489

## Sources

- ClinicalTrials.gov NCT00615602: https://clinicaltrials.gov/study/NCT00615602

## Connected records

- cancers: [Breast cancer (all types)](https://onco.cc/cancers/breast-cancer/)
- drugs: [Cyclophosphamide](https://onco.cc/drugs/cyclophosphamide/), [Docetaxel](https://onco.cc/drugs/docetaxel/), [Epirubicin](https://onco.cc/drugs/epirubicin/), [Fluorouracil (5-FU)](https://onco.cc/drugs/fluorouracil/), [Lenograstim](https://onco.cc/drugs/lenograstim/), [Pegfilgrastim](https://onco.cc/drugs/pegfilgrastim/), [Trastuzumab](https://onco.cc/drugs/trastuzumab/)

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JSON: https://onco.cc/api/v1/entities/nct00615602.json