# Combination Chemotherapy and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer

Source: https://onco.cc/trials/nct00628810/  
OnCo record `nct00628810` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 2 trial of UGT1A1 genotyping before irinotecan in Colorectal cancer, run by Federation Francophone de Cancerologie Digestive, completed.

## Summary

Combination Chemotherapy and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer is a phase 2 interventional study registered as NCT00628810 by Federation Francophone de Cancerologie Digestive, with 86 participants recorded, started 2007-01 and reaching its primary completion in 2008-01. Interventions recorded: bevacizumab, fluorouracil, irinotecan hydrochloride, leucovorin calcium. Conditions recorded: Colorectal Cancer.

Linked to the technology UGT1A1 genotyping before irinotecan because the registry's title names it ("ugt1a1 28") and Colorectal cancer among its conditions. Registry record only: no result has been read by an editor.

## Fields

- Kind: Trial
- Status: completed
- Last checked: 2026-09-22
- Tags: pipeline; ctgov-ingest
- Registry id: NCT00628810
- Phase: 2
- Setting: Chemotherapy With FOLFIRI Plus Bevacizumab (AvastinR) in Patients With Metastatic Colorectal Cancer Bearing Genotype UGT1A1*1/UGT1A1*1 or UGT1A1*1/UGT1A1*1/UGT1A1*28: Prospective, Phase II, Multicenter Study
- Sponsor: Federation Francophone de Cancerologie Digestive
- Enrolled: 86

## Sources

- ClinicalTrials.gov NCT00628810: https://clinicaltrials.gov/study/NCT00628810

## Connected records

- cancers: [Colorectal cancer](https://onco.cc/cancers/colorectal/)
- technologies: [UGT1A1 genotyping before irinotecan](https://onco.cc/technologies/ugt1a1-genotyping/)
- drugs: [Fluorouracil (5-FU)](https://onco.cc/drugs/fluorouracil/), [Irinotecan (and liposomal irinotecan)](https://onco.cc/drugs/irinotecan/), [Leucovorin (folinic acid)](https://onco.cc/drugs/leucovorin/)

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