# Cisplatin With or Without Sodium Thiosulfate in Treating Young Patients With Stage I, II, or III Childhood Liver Cancer

Source: https://onco.cc/trials/nct00652132/  
OnCo record `nct00652132` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of Cisplatin and Sodium thiosulfate in Hepatocellular carcinoma, run by University of Birmingham, completed.

## Summary

Cisplatin With or Without Sodium Thiosulfate in Treating Young Patients With Stage I, II, or III Childhood Liver Cancer is a phase 3 interventional study registered as NCT00652132 by University of Birmingham, with 116 participants recorded, started 2007-12-15 and reaching its primary completion in 2017-09-04. Interventions recorded: cisplatin, sodium thiosulfate. Conditions recorded: Liver Cancer, Ototoxicity.

Linked to the drug Sodium thiosulfate because the registry names it among its interventions and Hepatocellular carcinoma among its conditions. Registry record only: no result has been read by an editor.

## Fields

- Kind: Trial
- Status: completed
- Last checked: 2026-09-22
- Tags: pipeline; ctgov-ingest
- Registry id: NCT00652132
- Phase: 3
- Setting: A Multi-centre Open-label Randomised Phase III Trial of the Efficacy of Sodium Thiosulphate in Reducing Ototoxicity in Patients Receiving Cisplatin Chemotherapy for Standard Risk Hepatoblastoma
- Sponsor: University of Birmingham
- Enrolled: 116

## Sources

- ClinicalTrials.gov NCT00652132: https://clinicaltrials.gov/study/NCT00652132

## Connected records

- cancers: [Hepatocellular carcinoma](https://onco.cc/cancers/hcc/)
- drugs: [Cisplatin](https://onco.cc/drugs/cisplatin/), [Sodium thiosulfate (otoprotectant)](https://onco.cc/drugs/sodium-thiosulfate/)

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