# Tegafur-Uracil and Leucovorin or S-1 in Treating Patients With Stage III Colon Cancer That Has Been Completely Removed by Surgery

Source: https://onco.cc/trials/nct00660894/  
OnCo record `nct00660894` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of Leucovorin and Tegafur, gimeracil and oteracil in Colorectal cancer, run by Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan, completed.

## Summary

Tegafur-Uracil and Leucovorin or S-1 in Treating Patients With Stage III Colon Cancer That Has Been Completely Removed by Surgery is a phase 3 interventional study registered as NCT00660894 by Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan, with 1535 participants recorded, started 2008-04 and reaching its primary completion in 2012-06. Interventions recorded: folinate calcium, tegafur-uracil, tegafur-gimeracil-oteracil potassium. Conditions recorded: Colorectal Cancer.

Linked to the drug Tegafur, gimeracil and oteracil because the registry names it among its interventions and Colorectal cancer among its conditions. Registry record only: no result has been read by an editor.

## Fields

- Kind: Trial
- Status: completed
- Last checked: 2026-09-22
- Tags: pipeline; ctgov-ingest
- Registry id: NCT00660894
- Phase: 3
- Setting: Randomized Phase III Study of UFT+Leucovorin vs. TS-1 as Adjuvant Treatment for Stage III Colon Cancer, and Investigate Predictive Factors Based on Gene Expression
- Sponsor: Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
- Enrolled: 1535

## Sources

- ClinicalTrials.gov NCT00660894: https://clinicaltrials.gov/study/NCT00660894

## Connected records

- cancers: [Colorectal cancer](https://onco.cc/cancers/colorectal/)
- drugs: [Leucovorin (folinic acid)](https://onco.cc/drugs/leucovorin/), [Tegafur, gimeracil and oteracil (S-1)](https://onco.cc/drugs/tegafur-gimeracil-oteracil/)

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