# Video-Assisted Surgery or Talc Pleurodesis in Treating Patients With Malignant Mesothelioma

Source: https://onco.cc/trials/nct00821860/  
OnCo record `nct00821860` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of Talc in Mesothelioma and Metastatic cancer, run by Papworth Hospital NHS Foundation Trust, completed.

## Summary

Video-Assisted Surgery or Talc Pleurodesis in Treating Patients With Malignant Mesothelioma is a phase 3 interventional study registered as NCT00821860 by Papworth Hospital NHS Foundation Trust, with 196 participants recorded, started 2003-09 and reaching its primary completion in 2013-02. Interventions recorded: talc, therapeutic thoracoscopy, therapeutic videothoracoscopy. Conditions recorded: Malignant Mesothelioma, Metastatic Cancer.

Linked to the drug Talc because the registry names it among its interventions and Mesothelioma and Metastatic cancer among its conditions. Registry record only: no result has been read by an editor.

## Fields

- Kind: Trial
- Status: completed
- Last checked: 2026-09-22
- Tags: pipeline; ctgov-ingest
- Registry id: NCT00821860
- Phase: 3
- Setting: Prospective Randomised Controlled Trial of Video-Assisted Thoracoscopic (VAT) Cytoreductive Pleurectomy Compared to Talc Pleurodesis in Patients With Suspected or Proven Malignant Mesothelioma
- Sponsor: Papworth Hospital NHS Foundation Trust
- Enrolled: 196

## Sources

- ClinicalTrials.gov NCT00821860: https://clinicaltrials.gov/study/NCT00821860

## Connected records

- cancers: [Mesothelioma](https://onco.cc/cancers/mesothelioma/), [Metastatic cancer (cancer that has spread)](https://onco.cc/cancers/metastatic-cancer/)
- drugs: [Talc (intrapleural)](https://onco.cc/drugs/talc-sclerosant/)

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