# Methotrexate or Pentostatin for Graft-versus-host Disease Prophylaxis in Risk-adapted Allogeneic Bone Marrow Transplantation for Hematologic Malignancies

Source: https://onco.cc/trials/nct01188798/  
OnCo record `nct01188798` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of Methotrexate and Pentostatin in Acute lymphoblastic leukaemia and Leukaemia, run by St. Jude Children's Research Hospital, completed.

## Summary

Methotrexate or Pentostatin for Graft-versus-host Disease Prophylaxis in Risk-adapted Allogeneic Bone Marrow Transplantation for Hematologic Malignancies is a phase 3 interventional study registered as NCT01188798 by St. Jude Children's Research Hospital, with 6 participants recorded, started 2010-09 and reaching its primary completion in 2012-02. Interventions recorded: Methotrexate, Pentostatin. Conditions recorded: Acute Lymphoblastic Leukemia, Acute Myelocytic Leukemia, Chronic Myelocytic Leukemia, Hodgkin's Disease, Myelodysplastic Syndrome.

Linked to the drug Pentostatin because the registry names it among its interventions and Acute lymphoblastic leukaemia and Leukaemia among its conditions. Registry record only: no result has been read by an editor.

## Fields

- Kind: Trial
- Status: completed
- Last checked: 2026-09-22
- Tags: pipeline; ctgov-ingest
- Registry id: NCT01188798
- Phase: 3
- Setting: Methotrexate or Pentostatin for Graft-versus-host Disease Prophylaxis in Risk-adapted Allogeneic Bone Marrow Transplantation for Hematologic Malignancies
- Sponsor: St. Jude Children's Research Hospital
- Enrolled: 6

## Sources

- ClinicalTrials.gov NCT01188798: https://clinicaltrials.gov/study/NCT01188798

## Connected records

- cancers: [Acute lymphoblastic leukaemia](https://onco.cc/cancers/all-leukemia/), [Leukaemia (all types)](https://onco.cc/cancers/leukaemia/)
- drugs: [Methotrexate](https://onco.cc/drugs/methotrexate/), [Pentostatin](https://onco.cc/drugs/pentostatin/)

---
JSON: https://onco.cc/api/v1/entities/nct01188798.json