# SWOG S1207 endocrine therapy with or without everolimus

Source: https://onco.cc/trials/nct01674140/  
OnCo record `nct01674140` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

S1207 compares hormone therapy with or without everolimus after breast cancer treatment. It asks whether adding everolimus changes the chance of recurrence.

## Summary

S1207 compares hormone therapy with or without everolimus after breast cancer treatment. It asks whether adding everolimus changes the chance of recurrence.

Interventional study registered as NCT01674140, sponsored by SWOG Cancer Research Network. Registry phase: 3. Registry enrollment is 1,939 participants (actual). Registry status checked October 10, 2026: active not recruiting. UCSF lists this study as closed to local enrollment; local availability and overall registry status are separate. See the registry for full eligibility and current sites.

## Fields

- Kind: Trial
- Status: active
- Last checked: 2026-10-10
- Also known as: S1207 Hormone Therapy With or Without Everolimus in Treating Patients With Breast Cancer
- Tags: ucsf-breast-coverage; interventional
- Registry id: NCT01674140
- Phase: 3
- Setting: Hormone receptor-positive, HER2-negative high-risk breast cancer after surgery
- Sponsor: SWOG Cancer Research Network
- Enrolled: 1939

## Sources

- ClinicalTrials.gov NCT01674140: https://clinicaltrials.gov/study/NCT01674140
- UCSF study listing and local availability: https://clinicaltrials.ucsf.edu/trial/NCT01674140

## Connected records

- cancers: [Breast cancer (all types)](https://onco.cc/cancers/breast-cancer/)
- drugs: [Anastrozole](https://onco.cc/drugs/anastrozole/), [Everolimus](https://onco.cc/drugs/everolimus/), [Exemestane](https://onco.cc/drugs/exemestane/), [Goserelin / leuprolide (ovarian function suppression)](https://onco.cc/drugs/goserelin/), [Letrozole (and other aromatase inhibitors)](https://onco.cc/drugs/letrozole/), [Tamoxifen](https://onco.cc/drugs/tamoxifen/)
- institutions: [UCSF Helen Diller Family Comprehensive Cancer Center](https://onco.cc/institutions/ucsf/)

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