# Systemic Chemotherapy Combined With Recombinant Human Adenovirus Type 5 and Endostatin Injections for Treatment Malignant Hydrothorax in NSCLC Patients

Source: https://onco.cc/trials/nct02579564/  
OnCo record `nct02579564` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of Gemcitabine, Vinorelbine, Paclitaxel / nab-paclitaxel, Pemetrexed, H101 oncolytic adenovirus, Recombinant human endostatin and Cisplatin in Non-small-cell lung cancer, run by Xinqiao Hospital of Chongqing, with a status the registry has not verified recently.

## Summary

Systemic Chemotherapy Combined With Recombinant Human Adenovirus Type 5 and Endostatin Injections for Treatment Malignant Hydrothorax in NSCLC Patients is a phase 3 interventional study registered as NCT02579564 by Xinqiao Hospital of Chongqing, with 134 participants planned, started 2016-10 and due to reach its primary completion in 2018-06. Interventions recorded: Gemcitabine, Vinorelbine, Paclitaxel, Pemetrexed, Oncorine, Endostar, Cisplatin. Conditions recorded: Malignant Hydrothorax, Non Small Cell Lung Cancer.

Linked to the drug H101 oncolytic adenovirus because the registry names it among its interventions and Non-small-cell lung cancer among its conditions. Registry record only: no result has been read by an editor.

## Fields

- Kind: Trial
- Last checked: 2026-09-22
- Tags: pipeline; ctgov-ingest
- Registry id: NCT02579564
- Phase: 3
- Setting: Systemic Chemotherapy Combined With Thoracic Cavity Perfusion of Recombinant Human Adenovirus Type 5 and Endostatin Injections Versus Cisplatin for Treatment Malignant Hydrothorax in Non Small Cell Lung Cancer (NSCLC) Patients: A Multi-center, Randomized, Controlled Clinical Trial
- Sponsor: Xinqiao Hospital of Chongqing
- Enrolled: 134

## Sources

- ClinicalTrials.gov NCT02579564: https://clinicaltrials.gov/study/NCT02579564

## Connected records

- cancers: [Non-small-cell lung cancer](https://onco.cc/cancers/nsclc/)
- drugs: [Cisplatin](https://onco.cc/drugs/cisplatin/), [Gemcitabine](https://onco.cc/drugs/gemcitabine/), [H101 oncolytic adenovirus](https://onco.cc/drugs/h101-oncolytic-adenovirus/), [Paclitaxel / nab-paclitaxel](https://onco.cc/drugs/paclitaxel/), [Pemetrexed](https://onco.cc/drugs/pemetrexed/), [Recombinant human endostatin](https://onco.cc/drugs/recombinant-human-endostatin/), [Vinorelbine](https://onco.cc/drugs/vinorelbine/)

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