# Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma Multiforme

Source: https://onco.cc/trials/nct02685605/  
OnCo record `nct02685605` (Trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)"; commercial use needs a licence.

## TL;DR

A phase 3 trial of Intraoperative radiotherapy in Glioma & glioblastoma, run by Universitätsmedizin Mannheim, active and no longer recruiting.

## Summary

Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma Multiforme is a phase 3 interventional study registered as NCT02685605 by Universitätsmedizin Mannheim, with 314 participants planned, started 2016-12-09 and due to reach its primary completion in 2025-11. Interventions recorded: Standard surgery, Intraoperative radiotherapy, Radiochemotherapy, Temozolomide. Conditions recorded: Glioblastoma.

Linked to the technology Intraoperative radiotherapy because the registry names it ("intraoperative radiotherapy") among its interventions and Glioma & glioblastoma among its conditions. Registry record only: no result has been read by an editor.

## Fields

- Kind: Trial
- Status: active
- Last checked: 2026-09-22
- Tags: pipeline; ctgov-ingest
- Registry id: NCT02685605
- Phase: 3
- Setting: A Multicenter Randomized Phase III Trial on INTraoperative RAdiotherapy in Newly Diagnosed GliOblastoma Multiforme (INTRAGO II)
- Sponsor: Universitätsmedizin Mannheim
- Enrolled: 314

## Sources

- ClinicalTrials.gov NCT02685605: https://clinicaltrials.gov/study/NCT02685605

## Connected records

- cancers: [Glioma & glioblastoma](https://onco.cc/cancers/glioblastoma/)
- technologies: [Intraoperative radiotherapy (IORT)](https://onco.cc/technologies/intraoperative-radiotherapy/)
- drugs: [Temozolomide](https://onco.cc/drugs/temozolomide/)

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